Platelet-derived growth factor produced by pulmonary cells.
1991
A R Brody, and
J C Bonner
Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709.
UI
MeSH Term
Description
Entries
D008168
Lung
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Lungs
D010982
Platelet-Derived Growth Factor
Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.
A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.