| D007075 |
Immunoglobulin M |
A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally was called a macroglobulin. |
Gamma Globulin, 19S,IgM,IgM Antibody,IgM1,IgM2,19S Gamma Globulin,Antibody, IgM |
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| D008297 |
Male |
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Males |
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| D004797 |
Enzyme-Linked Immunosorbent Assay |
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed. |
ELISA,Assay, Enzyme-Linked Immunosorbent,Assays, Enzyme-Linked Immunosorbent,Enzyme Linked Immunosorbent Assay,Enzyme-Linked Immunosorbent Assays,Immunosorbent Assay, Enzyme-Linked,Immunosorbent Assays, Enzyme-Linked |
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| D005260 |
Female |
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Females |
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| D005732 |
Gangliosides |
A subclass of ACIDIC GLYCOSPHINGOLIPIDS. They contain one or more sialic acid (N-ACETYLNEURAMINIC ACID) residues. Using the Svennerholm system of abbrevations, gangliosides are designated G for ganglioside, plus subscript M, D, or T for mono-, di-, or trisialo, respectively, the subscript letter being followed by a subscript arabic numeral to indicated sequence of migration in thin-layer chromatograms. (From Oxford Dictionary of Biochemistry and Molecular Biology, 1997) |
Ganglioside,Sialoglycosphingolipids |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D016472 |
Motor Neuron Disease |
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) |
Anterior Horn Cell Disease,Familial Motor Neuron Disease,Lateral Sclerosis,Motor Neuron Disease, Lower,Motor Neuron Disease, Upper,Lower Motor Neuron Disease,Motor Neuron Disease, Familial,Motor Neuron Disease, Secondary,Motor System Disease,Primary Lateral Sclerosis,Secondary Motor Neuron Disease,Upper Motor Neuron Disease,Lateral Scleroses,Lateral Scleroses, Primary,Lateral Sclerosis, Primary,Motor Neuron Diseases,Motor System Diseases,Neuron Disease, Motor,Neuron Diseases, Motor,Primary Lateral Scleroses,Scleroses, Lateral,Scleroses, Primary Lateral,Sclerosis, Lateral,Sclerosis, Primary Lateral |
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| D020274 |
Autoimmune Diseases of the Nervous System |
Disorders caused by cellular or humoral immune responses primarily directed towards nervous system autoantigens. The immune response may be directed towards specific tissue components (e.g., myelin) and may be limited to the central nervous system (e.g., MULTIPLE SCLEROSIS) or the peripheral nervous system (e.g., GUILLAIN-BARRE SYNDROME). |
Antibody-Mediated Encephalitis,Autoimmune Encephalitis,Immune Disorders, Nervous System,Nervous System Autoimmune Diseases,Autoimmune Diseases, Nervous System,Autoimmune Diseases, Neurologic,Autoimmune Disorders of the Nervous System,Autoimmune Disorders, Nervous System,Autoimmune Nervous System Diseases,Immune Diseases, Nervous System,Nervous System Immune Diseases,Nervous System Immune Disorders,Neurologic Autoimmune Diseases,Antibody Mediated Encephalitis,Antibody-Mediated Encephalitides,Autoimmune Disease, Neurologic,Autoimmune Encephalitides,Encephalitis, Antibody-Mediated,Encephalitis, Autoimmune,Neurologic Autoimmune Disease |
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| D020277 |
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating |
A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337) |
CIDP,Chronic Inflammatory Demyelinating Polyradiculoneuropathy,Chronic Inflammatory Polyradiculoneuropathy,Inflammatory Polyradiculopathy, Chronic,Polyneuropathy, Inflammatory Demyelinating, Chronic,Polyradiculoneuropathy, Chronic Inflammatory,Chronic Inflammatory Polyradiculoneuropathies,Chronic Inflammatory Polyradiculopathies,Chronic Inflammatory Polyradiculopathy,Inflammatory Polyradiculoneuropathies, Chronic,Inflammatory Polyradiculoneuropathy, Chronic,Inflammatory Polyradiculopathies, Chronic,Polyradiculoneuropathies, Chronic Inflammatory,Polyradiculopathies, Chronic Inflammatory,Polyradiculopathy, Chronic Inflammatory |
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