Biomaterial Database

Injectable collagenase clostridium histolyticum for Dupuytren's contracture. 2009

Peng Zhang, and Ling Qin

UI	MeSH Term	Description	Entries
D003012	Microbial Collagenase	A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.	Clostridiopeptidase A,Clostridium histolyticum Collagenase,Collagenase, Microbial,Collagenase Clostridium histolyticum,Collagenase-Like Peptidase,Collalysine,Nucleolysin,Clostridium histolyticum, Collagenase,Collagenase Like Peptidase,Collagenase, Clostridium histolyticum,Peptidase, Collagenase-Like,histolyticum, Collagenase Clostridium
D004387	Dupuytren Contracture	A fibromatosis of the palmar fascia characterized by thickening and contracture of the fibrous bands on the palmar surfaces of the hand and fingers. It arises most commonly in men between the ages of 30 and 50.	Dupuytren's Contracture,Dupuytren's Disease,Fibromatosis, Palmar,Contracture, Dupuytren,Contracture, Dupuytren's,Dupuytren Disease,Dupuytrens Contracture,Dupuytrens Disease,Palmar Fibromatosis
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012421	Rupture	Forcible or traumatic tear or break of an organ or other soft part of the body.	Ruptures
D013708	Tendon Injuries	Injuries to the fibrous cords of connective tissue which attach muscles to bones or other structures.	Injuries, Tendon,Injury, Tendon,Tendon Injury
D015552	Injections, Intralesional	Injections introduced directly into localized lesions.	Intralesional Injections,Injection, Intralesional,Intralesional Injection
D047009	Clostridium histolyticum	A species of gram-positive, strongly proteolytic bacteria in the family Clostridiaceae. It contains several forms of COLLAGENASE whose action can lead to GAS GANGRENE in humans and HORSES.