BIOMAT Database Logo BIOMAT Database Logo

Role of Oct-4 during acquisition of developmental competence in mouse oocyte. 2009

Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
Sezione di Istologia ed Embriologia, Dipartimento di Medicina Sperimentale, Universita' degli Studi di Parma, Parma, Italy.

Knowledge of what determines the developmental competence of oocytes during folliculogenesis is poor. This review, through the analysis of the expression profile of developmentally competent or incompetent mouse oocytes, summarizes the results of recent studies showing that the Oct-4 transcription factor regulating the expression of Stella and Foxj2 at the Nanog locus could play a pivotal role in the establishment of the oocyte's developmental competence.

UI MeSH Term Description Entries
D009865 Oocytes Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM). Ovocytes,Oocyte,Ovocyte
D011506 Proteins Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. Gene Products, Protein,Gene Proteins,Protein,Protein Gene Products,Proteins, Gene
D002868 Chromosomal Proteins, Non-Histone Nucleoproteins, which in contrast to HISTONES, are acid insoluble. They are involved in chromosomal functions; e.g. they bind selectively to DNA, stimulate transcription resulting in tissue-specific RNA synthesis and undergo specific changes in response to various hormones or phytomitogens. Non-Histone Chromosomal Proteins,Chromosomal Proteins, Non Histone,Chromosomal Proteins, Nonhistone,Non-Histone Chromosomal Phosphoproteins,Chromosomal Phosphoproteins, Non-Histone,Non Histone Chromosomal Phosphoproteins,Non Histone Chromosomal Proteins,Nonhistone Chromosomal Proteins,Proteins, Non-Histone Chromosomal
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D050814 Octamer Transcription Factor-3 An octamer transcription factor that is expressed primarily in totipotent embryonic STEM CELLS and GERM CELLS and is down-regulated during CELL DIFFERENTIATION. Oct-3 Transcription Factor,Transcription Factor Oct-3,Oct-4 Transcription Factor,Octamer-Binding Protein 4,POU Domain, Class 5, Transcription Factor 1,POU5F1 Transcription Factor,Transcription Factor Oct-4,Oct 3 Transcription Factor,Oct 4 Transcription Factor,Oct-3, Transcription Factor,Oct-4, Transcription Factor,Octamer Binding Protein 4,Octamer Transcription Factor 3,Transcription Factor Oct 3,Transcription Factor Oct 4,Transcription Factor, Oct-3,Transcription Factor, Oct-4,Transcription Factor, POU5F1,Transcription Factor-3, Octamer
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus
D051858 Forkhead Transcription Factors A subclass of winged helix DNA-binding proteins that share homology with their founding member fork head protein, Drosophila. Forkhead Box Protein,Forkhead Box Transcription Factor,Forkhead Protein,Forkhead Transcription Factor,Forkhead Box Proteins,Forkhead Box Transcription Factors,Forkhead Proteins,Fox Transcription Factors,Box Protein, Forkhead,Box Proteins, Forkhead,Factor, Forkhead Transcription,Protein, Forkhead,Protein, Forkhead Box,Proteins, Forkhead Box,Transcription Factor, Forkhead,Transcription Factors, Forkhead,Transcription Factors, Fox
D018507 Gene Expression Regulation, Developmental Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism. Developmental Gene Expression Regulation,Embryologic Gene Expression Regulation,Gene Expression Regulation, Embryologic,Regulation of Gene Expression, Developmental,Regulation of Gene Expression, Embryologic,Regulation, Gene Expression, Developmental,Regulation, Gene Expression, Embryologic

Related Publications

Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
The role of progesterone in oocyte acquisition of developmental competence.
August 2012, Reproduction in domestic animals = Zuchthygiene,
Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
Bovine oocyte maturation: acquisition of developmental competence.
January 2019, Reproduction, fertility, and development,
Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
Follicular oocyte growth and acquisition of developmental competence.
October 2003, Animal reproduction science,
Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
Acquisition and loss of oocyte meiotic and developmental competence during in vitro antral follicle growth in mouse.
May 2010, Fertility and sterility,
Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
Gonadotropins affect Oct-4 gene expression during mouse oocyte growth.
June 2006, Molecular reproduction and development,
Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
Can patterns of oocyte granulation telegraph the acquisition of developmental competence?
August 2021, Fertility and sterility,
Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
Disruption of bidirectional oocyte-cumulus paracrine signaling during in vitro maturation reduces subsequent mouse oocyte developmental competence.
May 2009, Biology of reproduction,
Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
The Role of Oocyte Organelles in Determining Developmental Competence.
September 2017, Biology,
Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
Hyperglycaemia and lipid differentially impair mouse oocyte developmental competence.
May 2015, Reproduction, fertility, and development,
Maurizio Zuccotti, and Valeria Merico, and Carlo Alberto Redi, and Riccardo Bellazzi, and James Adjaye, and Silvia Garagna
Oocyte-secreted factors enhance oocyte developmental competence.
August 2006, Developmental biology,
Copied contents to your clipboard!