BIOMAT Database Logo BIOMAT Database Logo

Occurrence of IgG antibodies to Anaplasma phagocytophilum in humans suspected of Lyme borreliosis in eastern Slovakia. 2009

Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
Department of Public Health, Pavol Jozef Safarik University, Faculty of Medicine, Srobarova 2, 041 80 Kosice, Slovak Republic. zuzana.kalinova@upjs.sk

Human granulocytic anaplasmosis (HGA) and Lyme borreliosis (LB) are tick-borne and emerging infectious diseases caused by the Anaplasma phagocytophilum and Borrelia burgdorferi species. In Europe, including Slovakia, the principal vector of both pathogens is the common tick - Ixodes ricinus, in which double infections with these pathogens have been reported. The aim of our study was evidence of IgG antibodies against A. phagocytophilum in blood sera of humans with suspects LB from several Clinics of University Hospitals, and the evaluation of the possibility of B. burgdorferi and A. phagocytophilum co-infection in examined patients. The serological method ELISA was used to detect IgM and IgG antibodies against B. burgdorferi. Anti-A. phagocytophilum IgG antibodies were analyzed by the A. phagocytophilum Indirect Immunofluorescence Antibody (IFA) IgG test. A total of 214 human samples (91 men, 123 women) were obtained from patients living in Kosice town and in villages around Kosice (Eastern Slovakia). IgG antibodies against A. phagocytophilum were detected in 15 cases (6 men, 9 women), which represented 7.0 % positivity. Two cases of the co-infection B. burgdorferi with A. phagocytophilum, which equals 0.93 % of the total number, were found.

UI MeSH Term Description Entries
D007074 Immunoglobulin G The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B. Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008193 Lyme Disease An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut. Lyme Borreliosis,B. burgdorferi Infection,Borrelia burgdorferi Infection,Lyme Arthritis,Arthritis, Lyme,B. burgdorferi Infections,Borrelia burgdorferi Infections,Borreliosis, Lyme,Disease, Lyme
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
[Seroprevalence of Anaplasma phagocytophilum in patients with suspected Lyme borreliosis].
November 2014, Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne,
Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
Anaplasma phagocytophilum infection in patients with early Lyme borreliosis, erythema migrans, in north-eastern Poland.
December 2009, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases,
Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
Occurrence of antibodies to Anaplasma phagocytophilum in patients with suspected tick-borne encephalitis.
January 2015, Annals of agricultural and environmental medicine : AAEM,
Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
[Lyme borreliosis and co-infections. Place of Anaplasma phagocytophilum and Bartonella henselae].
January 2015, Bulletin de l'Academie nationale de medecine,
Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
Anaplasma phagocytophilum antibodies in humans, Japan, 2010-2011.
March 2014, Emerging infectious diseases,
Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
Assessment of Anaplasma phagocytophilum presence in early Lyme borreliosis manifested by erythema migrans skin lesions.
January 2020, Travel medicine and infectious disease,
Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
Reduced number of interleukin-12 secreting cells in patients with Lyme borreliosis previously exposed to Anaplasma phagocytophilum.
February 2006, Clinical and experimental immunology,
Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
Assessment of antibodies against surface and outer membrane proteins of Anaplasma phagocytophilum in Lyme borreliosis and tick-borne encephalitis paediatric patients.
September 2016, Epidemiology and infection,
Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
Serological screening of occurrence of antibodies to Encephalitozoon cuniculi in humans and animals in Eastern Slovakia.
January 2003, Annals of agricultural and environmental medicine : AAEM,
Zuzana Kalinova, and Monika Halanova, and Lydia Cislakova, and Zlatana Sulinova, and Pavol Jarcuska
[Diagnosis of Lyme borreliosis. How to corroborate suspected borreliosis].
April 2000, MMW Fortschritte der Medizin,
Copied contents to your clipboard!