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Prevalence of systemic sclerosis in Split-Dalmatia county in Southern Croatia. 2010

Mislav Radić, and Dusanka Martinović Kaliterna, and Damir Fabijanić, and Josipa Radić
Department of Internal Medicine, University Hospital Split, Split, Croatia. mislavradic@gmail.com

This study aims to evaluate the prevalence of patients with systemic sclerosis (SSc) in Split-Dalmatia County in Southern Croatia. Patients were recruited from the medical records of University Hospital Split. Our Department of Rheumatology and Clinical Immunology is the only tertiary referral center for the Split-Dalmatia County, which has a population of 313,365 inhabitants aged over 18 years. Diagnoses were verified by medical record review. Cases of localized scleroderma (morphea and linear disease) were excluded. All patients were re-evaluated by the American College of Rheumatology (ACR) criteria for the classification of systemic sclerosis. Prevalence of SSc in Split-Dalmatia County was estimated at 15.6 cases among 100,000 adults (95%CI 11.8-19.4). The prevalence of SSc in Split-Dalmatia County in Southern Croatia according only to the ACR criteria is higher than in other European countries. These data should facilitate research regarding the role of geographic and environmental factors for this disease in comparison populations.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D012595 Scleroderma, Systemic A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA. Sclerosis, Systemic,Systemic Scleroderma,Systemic Sclerosis
D015995 Prevalence The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time. Period Prevalence,Point Prevalence,Period Prevalences,Point Prevalences,Prevalence, Period,Prevalence, Point,Prevalences
D017523 Croatia Created 7 April 1992 as a result of the division of Yugoslavia.

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