-transparent.png){kind=logo}
The clinical diagnosis of Lyme borreliosis is easily established in the initial phase of the illness. Erythema chronicum migrans is pathognomonic of this infection. However, during further complications (neurological, cardiac or articular) the diagnosis is chiefly based on laboratory results. The detection of specific antibodies to B. burgdorferi is one of the effective means of confirming the diagnosis. Culture or isolation of this bacteria is not routinely performed due to its very low yield. In this article a case of serologically proved neuro-borreliosis is described and the methods of diagnosis are discussed. Intrathecal synthesis of antibodies observed in the cerebrospinal fluid of this patient and the specificity of serologic tests confirmed by Western-blot provide the diagnosis. However, the absence of locally synthesized antibodies in the cerebrospinal fluid is not sufficient to rule out neuro-borreliosis.
O Péter, and
M Marini, and
E Blanc, and
G Dupuis
December 1992,
Italian journal of neurological sciences,
O Péter, and
M Marini, and
E Blanc, and
G Dupuis
January 1991,
Infection,
O Péter, and
M Marini, and
E Blanc, and
G Dupuis
January 1991,
Scandinavian journal of infectious diseases. Supplementum,
O Péter, and
M Marini, and
E Blanc, and
G Dupuis
June 1995,
Versicherungsmedizin,
O Péter, and
M Marini, and
E Blanc, and
G Dupuis
April 2015,
Praxis,
O Péter, and
M Marini, and
E Blanc, and
G Dupuis
July 2005,
Clinical microbiology reviews,
O Péter, and
M Marini, and
E Blanc, and
G Dupuis
January 2007,
Medecine et maladies infectieuses,
O Péter, and
M Marini, and
E Blanc, and
G Dupuis
July 1988,
Beitrage zur Orthopadie und Traumatologie,
O Péter, and
M Marini, and
E Blanc, and
G Dupuis
June 2017,
MMW Fortschritte der Medizin,
O Péter, and
M Marini, and
E Blanc, and
G Dupuis
March 2021,
Clinical microbiology reviews,
