[Hemoglobin concentration and iron stores in female blood donors]. 1991

J Dalhøj, and P Wiggers
Arvepatologisk Institut, Odense Universitet.

The blood hemoglobin concentration (B-Hb) and iron indices were measured in 1,856 consecutive female blood donors. The blood hemoglobin distribution was Gaussian except for an excess of high values. According to criteria defined by the WHO, 9.5% of the population were anemic, but using several criteria only 0.9% had iron deficiency anemia in agreement with the blood hemoglobin distribution curve. The distribution of the S-ferritin values was log Gaussian. Nearly 1/5 of female blood donors had low iron stores despite widespread use of iron supplements. The weak correlation detected between the B-Hb values and the S-ferritin level points to an increased risk of anemia in female blood donors. Regular determination of the S-ferritin level in female blood donors or extended use of iron supplements may contribute to the establishment of adequate iron stores and hence the prevention of anemia.

UI MeSH Term Description Entries
D007501 Iron A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. Iron-56,Iron 56
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D001782 Blood Donors Individuals supplying blood or blood components for transfer to histocompatible recipients. Blood Donor,Donor, Blood,Donors, Blood
D005260 Female Females
D005293 Ferritins Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types. Basic Isoferritin,Ferritin,Isoferritin,Isoferritin, Basic
D006454 Hemoglobins The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements. Eryhem,Ferrous Hemoglobin,Hemoglobin,Hemoglobin, Ferrous
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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