Meniscal transplantation in the human knee: a preliminary report. 1991

J C Garrett, and R N Steensen, and R N Stevensen

Meniscectomy can result in degenerative disease, with younger patients developing problems in middle age (1). In addition, loss of a major portion of a medical meniscus may increase instability in an anterior cruciate deficient knee (2). For these two reasons, it is theoretically desirable to transplant menisci in selected patients. In this paper, six patients who underwent allograft transplantation of a meniscus (four medial and two lateral) are presented to demonstrate the apparent success of the operative procedure. Follow-up extends from 24 to 44 months, June 1986 to March 1988. All patients are free of episodes of locking. Four have undergone arthroscopy, which demonstrated healing of the meniscus and no evidence of shrinkage. KT 1,000 values returned to normal in four cases, with concomitant reconstruction of the anterior cruciate ligament (ACL). It is hoped that meniscal transplantation will offset the development of degenerative changes; however, this supposition will remain unproven for decades. Meniscal transplantation seemed to improve stability in the knees undergoing ACL reconstruction. Arthroscopy performed after transplantation revealed that healing does indeed occur. There was no evidence of rejection, confirming the feeling that meniscal tissue is "immunologically privileged." Meniscal transplantation is offered as an adjunct to other reconstructive procedures in cases of meniscal deficient knees.

UI MeSH Term Description Entries
D007718 Knee Injuries Injuries to the knee or the knee joint. Injuries, Knee,Injury, Knee,Knee Injury
D008297 Male Males
D008592 Menisci, Tibial The interarticular fibrocartilages of the superior surface of the tibia. Lateral Menisci,Medial Menisci,Menisci, Lateral,Menisci, Medial,Semilunar Cartilages,Tibial Menisci,Meniscus, Medial,Meniscus, Tibial,Tibial Meniscus,Cartilage, Semilunar,Cartilages, Semilunar,Lateral Meniscus,Medial Meniscus,Meniscus, Lateral,Semilunar Cartilage
D010003 Osteoarthritis A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. Arthritis, Degenerative,Osteoarthrosis,Osteoarthrosis Deformans,Arthroses,Arthrosis,Arthritides, Degenerative,Degenerative Arthritides,Degenerative Arthritis,Osteoarthritides,Osteoarthroses
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006085 Graft Survival The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. Graft Survivals,Survival, Graft,Survivals, Graft
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000070600 Tibial Meniscus Injuries Injuries to the TIBIAL MENISCUS of the leg. Bucket Handle Tears,Flap Tears,Tibial Meniscus Tears,Torn Tibial Meniscus,Bucket Handle Tear,Flap Tear,Injuries, Tibial Meniscus,Injury, Tibial Meniscus,Meniscus Injuries, Tibial,Meniscus Injury, Tibial,Meniscus Tear, Tibial,Meniscus Tears, Tibial,Meniscus, Torn Tibial,Tear, Tibial Meniscus,Tears, Flap,Tears, Tibial Meniscus,Tibial Meniscus Injury,Tibial Meniscus Tear,Tibial Meniscus, Torn
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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