Neoplastic disease of the vertebral column: radiologic-pathologic correlation. 2010

Andrew M Zbojniewicz, and James Hartel, and Thuan Nguyen, and Kate Wilks, and Andrew Mace, and Jeffery P Hogg
Department of Radiology, West Virginia University, Morgantown, WV 26506, USA. andrew.zbojniewicz@cchmc.org

Spine imaging is frequently performed in daily practice. Due to the high frequency of spine examinations and the multiple modalities (ie, radiography, computed tomography, magnetic resonance imaging, positron emission tomography/computed tomography, single-photon emission computed tomography/computed tomography) used for imaging, neoplastic disease of the vertebral column will occasionally be encountered by practicing radiologists. When a lesion in the spine is encountered, it is helpful to have an understanding of the general types of pathology and key differentiating features that may aid in guiding appropriate workup (eg, no follow-up required, short-term follow-up, or directed biopsy). This article aims to provide a framework for characterizing neoplastic disease in the spine and allows the practicing radiologist an opportunity to develop a more concise and accurate differential diagnosis with which to guide clinical management.

UI MeSH Term Description Entries
D010001 Osteitis Deformans A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass. The resultant architecture of the bone assumes a mosaic pattern in which the fibers take on a haphazard pattern instead of the normal parallel symmetry. Paget's Disease of Bone,Osseous Paget's Disease,Paget Disease of Bone,Paget Disease, Bone,Pagets Disease, Bone
D010017 Osteoma, Osteoid A benign osteoblastic tumor with central vascularized nidus surrounded by normal reactive bone. It occurs especially in second decade of life most commonly in the femoral neck but can occur in any bone and any site within a bone. Osteoid Osteoma,Osteoid Osteomas,Osteomas, Osteoid
D011877 Radionuclide Imaging The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph. Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D002817 Chordoma A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed) Chordomas
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006391 Hemangioma A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000) Angioma,Chorioangioma,Hemangioma, Histiocytoid,Hemangioma, Intramuscular,Chorangioma,Chorangiomas,Chorioangiomas,Hemangiomas,Hemangiomas, Histiocytoid,Hemangiomas, Intramuscular,Histiocytoid Hemangioma,Histiocytoid Hemangiomas,Intramuscular Hemangioma,Intramuscular Hemangiomas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000465 Algorithms A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task. Algorithm
D012598 Sclerosis A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve. Scleroses
D013125 Spinal Neoplasms New abnormal growth of tissue in the SPINE. Neoplasm, Spinal,Neoplasms, Spinal,Spinal Neoplasm

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