A revision of Leptotheca Thélohan, 1895 is presented. The boundaries that separate Leptotheca from Ceratomyxa Thélohan, 1892 and Sphaerospora Thélohan, 1892 are vague and have been highlighted as an area of concern within myxosporean classification. A survey of the literature revealed 63 species that are currently assigned to Leptotheca and a further 11 species that have been relegated as synonyms in Ceratomyxa, Sphaerospora or Myxobolus Bütschli, 1882. The placement of some species in the genus is unclear and demonstrates the need for a revision. The type-species of Leptotheca (L. agilis Thélohan 1892) has many Ceratomyxa-like characters, such that a minor amendation of the diagnosis of Ceratomyxa will then accept the type-species of Leptotheca, rendering the latter genus its synonym. We propose the suppression of Leptotheca, with all species currently assigned to that genus reassigned to Ceratomyxa, Ellipsomyxa Køie, 2003, Myxobolus or Sphaerospora on the basis of appropriate morphological and biological traits. The diagnoses of Ceratomyxa and Ellipsomyxa are amended appropriately. Molecular analysis may change the placement of some species in the future; however, the aim of this review was to eliminate the ambiguity of assignment of species in the genera Leptotheca, Ceratomyxa and Sphaerospora by suppressing Leptotheca.