Testicular function of men occupationally exposed to para-tertiary butyl benzoic acid. 1981

M D Whorton, and H A Stubbs, and A Obrinsky, and T H Milby
Environmental Health Associates, Inc, 2150 Shattuck Avenue, Suite 414, Berkeley, CA 94704, USA.

The possible testicular effects resulting from occupational exposure to para-tertiary butyl benzoic acid (p-TBBA) were studied in 90 male volunteers employed at the Martinez, California, facility of the Shell Chemical Company. The comparison data used were obtained from an external reference group of 103 male volunteers not exposed to any known testicular toxin. Exposure indices were based on the calendar years of employment in a given job category. Outcome variables included sperm count, history of fathering children, and gonadotropin levels. It was concluded that p-TBBA, at the levels of exposure experienced at this plant, does not have an apparent clinical or epidemiologic effect on testicular function.

UI MeSH Term Description Entries
D007248 Infertility, Male The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility. Sterility, Male,Sub-Fertility, Male,Subfertility, Male,Male Infertility,Male Sterility,Male Sub-Fertility,Male Subfertility,Sub Fertility, Male
D008297 Male Males
D002140 California State bounded on the east by Nevada and Arizona, on the south by Mexico and the Pacific Ocean on the south and west, and on the north by Oregon.
D002617 Chemical Industry The aggregate enterprise of manufacturing and technically producing chemicals. (From Random House Unabridged Dictionary, 2d ed) Industry, Chemical,Chemical Industries,Industries, Chemical
D006062 Gonadotropins Hormones that stimulate gonadal functions such as GAMETOGENESIS and sex steroid hormone production in the OVARY and the TESTIS. Major gonadotropins are glycoproteins produced primarily by the adenohypophysis (GONADOTROPINS, PITUITARY) and the placenta (CHORIONIC GONADOTROPIN). In some species, pituitary PROLACTIN and PLACENTAL LACTOGEN exert some luteotropic activities. Gonadotropin
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001565 Benzoates Derivatives of BENZOIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxybenzene structure. Benzoate,Benzoic Acids,Acids, Benzoic
D013076 Sperm Count A count of SPERM in the ejaculum, expressed as number per milliliter. Sperm Number,Count, Sperm,Counts, Sperm,Number, Sperm,Numbers, Sperm,Sperm Counts,Sperm Numbers
D013733 Testicular Diseases Pathological processes of the TESTIS. Disease, Testicular,Diseases, Testicular,Testicular Disease
D016273 Occupational Exposure The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation. Exposure, Occupational,Exposures, Occupational,Occupational Exposures

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