Biomaterial Database

Effects of surgery on the phonation threshold pressure in patients with vocal fold polyps. 2010

Tyng-Guey Wang, and Yio-Wha Shau, and Tzu-Yu Hsiao

Department of Rehabilitation, National Taiwan University Hospital and National Taiwan University, College of Medicine, Taipei, Taiwan.

OBJECTIVE There are few objective measurements to assess the results of surgery for vocal fold polyps. This study investigated the effects of surgery on the phonation threshold pressure (PTP) in patients with vocal fold polyps. METHODS Prospectively, 32 consecutive patients with vocal fold polyps were enrolled. PTP was measured 1 day before and 6 weeks after laryngomicrosurgery, by means of an airflow interruption method. An accelerometer was used to detect the vocal fold vibration instead of using an acoustic signal. RESULTS In all 32 patients, the average preoperative PTP was 0.51 +/- 0.23 kPa, and 6 weeks after surgery, it was 0.28 +/- 0.17 kPa; this difference was statistically significant (p < 0.001). Individually, PTP decreased in 31 patients after surgery. PTP increased after surgery in only one patient, from 0.74 to 0.75 kPa. Subjectively, all patients could phonate with less effort after surgery. Use of an accelerometer to sense vocal fold vibration was feasible and made it easier to identify the time point of cessation of vocal fold vibration, which is important for PTP measurement. CONCLUSIONS Laryngomicrosurgery can lower PTP in patients with vocal fold polyps and improve the ease of phonation. PTP is one of the objective measurements for assessing the effects of surgery in patients with vocal fold polyps. Use of an accelerometer to detect vocal fold vibration improved the measurement of PTP.

UI	MeSH Term	Description	Entries
D007818	Laryngeal Diseases	Pathological processes involving any part of the LARYNX which coordinates many functions such as voice production, breathing, swallowing, and coughing.	Laryngeal Perichondritis,Larynx Diseases,Disease, Laryngeal,Disease, Larynx,Diseases, Laryngeal,Diseases, Larynx,Laryngeal Disease,Laryngeal Perichondritides,Larynx Disease,Perichondritides, Laryngeal,Perichondritis, Laryngeal
D007825	Laryngectomy	Total or partial excision of the larynx.	Laryngectomies
D007828	Laryngoscopy	Examination, therapy or surgery of the interior of the larynx performed with a specially designed endoscope.	Laryngoscopic Surgical Procedures,Surgical Procedures, Laryngoscopic,Laryngoscopic Surgery,Surgery, Laryngoscopic,Laryngoscopic Surgeries,Laryngoscopic Surgical Procedure,Laryngoscopies,Procedure, Laryngoscopic Surgical,Procedures, Laryngoscopic Surgical,Surgeries, Laryngoscopic,Surgical Procedure, Laryngoscopic
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010699	Phonation	The process of producing vocal sounds by means of VOCAL CORDS vibrating in an expiratory blast of air.	Phonations
D011127	Polyps	Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.	Polyp
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D004867	Equipment Design	Methods and patterns of fabricating machines and related hardware.	Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs
D005260	Female		Females