Stable reconstruction of piecewise continuous plane stratified biological tissues via electrical impedance tomography. 2010

Madlena Dolgin, and Pinchas D Einziger
Engineering School, Kinneret College on the Sea of Galilee, Israel. madlena@tx.technion.ac.il

Image reconstruction in electrical impedance tomography is, generally, an ill-posed nonlinear inverse problem. Regularization methods are widely used to ensure a stable solution. Herein, we present a case study, which uses a novel electrical impedance tomography method for reconstruction of layered biological tissues with piecewise continuous plane-stratified profiles. The algorithm implements the recently proposed reconstruction scheme for piecewise constant conductivity profiles, utilizing Legendre expansion in conjunction with improved Prony method. It is shown that the proposed algorithm is capable of successfully reconstructing piecewise continuous conductivity profiles with moderate slop. This reconstruction procedure, which calculates both the locations and the conductivities, repetitively provides inhomogeneous depth discretization, i.e., the depths grid is not equispaced. Incorporation of this specific inhomogeneous grid in the widely used mean least square reconstruction procedure results in a stable and accurate reconstruction, whereas, the commonly selected equispaced depth grid leads to unstable reconstruction. This observation establishes the main result of our investigation, highlighting the impact of physical phenomenon (the image series expansion) on electrical impedance tomography, leading to a physically motivated stabilization of the inverse problem, i.e., an inhomogeneous depth discretization renders an inherent regularization of the mean least square algorithm. The effectiveness and the significance of inhomogeneous discretization in electrical impedance tomography reconstruction procedure is further demonstrated and verified via numerical simulations.

UI MeSH Term Description Entries
D007089 Image Enhancement Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level. Image Quality Enhancement,Enhancement, Image,Enhancement, Image Quality,Enhancements, Image,Enhancements, Image Quality,Image Enhancements,Image Quality Enhancements,Quality Enhancement, Image,Quality Enhancements, Image
D007090 Image Interpretation, Computer-Assisted Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease. Image Interpretation, Computer Assisted,Computer-Assisted Image Interpretation,Computer-Assisted Image Interpretations,Image Interpretations, Computer-Assisted,Interpretation, Computer-Assisted Image,Interpretations, Computer-Assisted Image
D008954 Models, Biological Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment. Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D010992 Plethysmography, Impedance Recording changes in electrical impedance between electrodes placed on opposite sides of a part of the body, as a measure of volume changes in the path of the current. (Stedman, 25th ed) Rheography,Impedance Plethysmography,Impedance Plethysmographies,Plethysmographies, Impedance,Rheographies
D003198 Computer Simulation Computer-based representation of physical systems and phenomena such as chemical processes. Computational Modeling,Computational Modelling,Computer Models,In silico Modeling,In silico Models,In silico Simulation,Models, Computer,Computerized Models,Computer Model,Computer Simulations,Computerized Model,In silico Model,Model, Computer,Model, Computerized,Model, In silico,Modeling, Computational,Modeling, In silico,Modelling, Computational,Simulation, Computer,Simulation, In silico,Simulations, Computer
D000465 Algorithms A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task. Algorithm
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity
D014054 Tomography Imaging methods that result in sharp images of objects located on a chosen plane and blurred images located above or below the plane. Tomographies
D015203 Reproducibility of Results The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results. Reliability and Validity,Reliability of Result,Reproducibility Of Result,Reproducibility of Finding,Validity of Result,Validity of Results,Face Validity,Reliability (Epidemiology),Reliability of Results,Reproducibility of Findings,Test-Retest Reliability,Validity (Epidemiology),Finding Reproducibilities,Finding Reproducibility,Of Result, Reproducibility,Of Results, Reproducibility,Reliabilities, Test-Retest,Reliability, Test-Retest,Result Reliabilities,Result Reliability,Result Validities,Result Validity,Result, Reproducibility Of,Results, Reproducibility Of,Test Retest Reliability,Validity and Reliability,Validity, Face
D017097 Electric Impedance The resistance to the flow of either alternating or direct electrical current. Bioelectrical Impedance,Electric Resistance,Impedance,Ohmic Resistance,Biolectric Impedance,Electrical Impedance,Electrical Resistance,Impedance, Bioelectrical,Impedance, Biolectric,Impedance, Electric,Impedance, Electrical,Ohmic Resistances,Resistance, Electric,Resistance, Electrical,Resistance, Ohmic,Resistances, Ohmic

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