OBJECTIVE The aim of this article is to analyze the relation between dispositional optimism and coping with chronic pain. The study seeks to define the relation between life orientation (optimism vs. pessimism) and coping with pain (believes about pain control and the choice of coping strategy). METHODS The following questionnaires were used: LOT-R - Life Orientation Test, BPCQ - The Beliefs about Pain Control Questionnaire and CSQ - The Pain Coping Strategies Questionnaire. RESULTS The results show that dispositional optimism correlates positively with: internal locus of pain control r=0.6, P<0.01; declared coping with pain r=0.38, P<0.05; diverting attention r = 0.93, P<0.01; and behavioral activity r = 0.82, P<0.01. Dispositional optimism correlates negatively with catastrophizing r = -0.28, P<0.05. CONCLUSIONS We conclude that dispositional optimism plays a key role in forming the mechanisms of coping with chronic pain and thereby in improving the psychophysical comfort of patients.