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Preparation of the Major Urinary Metabolite of (-)-Prostaglandin E(2). 2009

Douglass F Taber, and Peiming Gu
Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716.

The best way to measure whole body production of the locally acting hormone prostaglandin E(2) (PGE(2)) is to assess the accumulation of the major urinary metabolite, PGE(2) U (M). A practical preparation of this delicate diacid is described. This synthetic PGE(2)U(M) will enable production of the antibodies that will be used to quantify this key metabolite.

UI MeSH Term Description Entries

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