Reorganization of global form and motion processing during human visual development. 2010

John Wattam-Bell, and Dee Birtles, and Pär Nyström, and Claes von Hofsten, and Kerstin Rosander, and Shirley Anker, and Janette Atkinson, and Oliver Braddick
Visual Development Unit, Department of Developmental Science, University College London, London WC1E 6BT, UK. j.wattam-bell@ucl.ac.uk <j.wattam-bell@ucl.ac.uk>

The functional selectivity of human primary visual cortex (V1) for orientation and motion direction is established by around 3 months of age [1-3], but there have been few studies of the development of extrastriate visual areas that integrate outputs from V1 [4-8]. We investigated sensitivity and topographical organization for global form and motion with high-density visual event-related potentials (VERPs) in 4- to 5-month-old infants and adults. Responses were measured to transitions between concentrically organized elements (short arc segments for form, dot trajectories for motion) and random arrangements. Adults showed topographically separate responses, with midline motion and more lateral form responses. Of 26 infants, 25 showed significant motion responses but only 13 showed form responses, suggesting more advanced development for extrastriate motion areas than form. Infants' form and motion responses were topographically distinct but contrasted with the corresponding adult topographies, with infants' motion responses more lateral than form responses. These results imply distinct neural sources at both ages and raise the possibility of substantial reorganization of extrastriate networks between infancy and adulthood. We speculate that global motion responses arise from area V5 in infants but are dominated by more medial areas such as V3/V3A and V6 in adults.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D010364 Pattern Recognition, Visual Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs. Recognition, Visual Pattern,Visual Pattern Recognition
D002657 Child Development The continuous sequential physiological and psychological maturing of an individual from birth up to but not including ADOLESCENCE. Infant Development,Development, Child,Development, Infant
D005074 Evoked Potentials, Visual The electric response evoked in the cerebral cortex by visual stimulation or stimulation of the visual pathways. Visual Evoked Response,Evoked Potential, Visual,Evoked Response, Visual,Evoked Responses, Visual,Potential, Visual Evoked,Potentials, Visual Evoked,Response, Visual Evoked,Responses, Visual Evoked,Visual Evoked Potential,Visual Evoked Potentials,Visual Evoked Responses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012684 Sensory Thresholds The minimum amount of stimulus energy necessary to elicit a sensory response. Sensory Threshold,Threshold, Sensory,Thresholds, Sensory
D014793 Visual Cortex Area of the OCCIPITAL LOBE concerned with the processing of visual information relayed via VISUAL PATHWAYS. Area V2,Area V3,Area V4,Area V5,Associative Visual Cortex,Brodmann Area 18,Brodmann Area 19,Brodmann's Area 18,Brodmann's Area 19,Cortical Area V2,Cortical Area V3,Cortical Area V4,Cortical Area V5,Secondary Visual Cortex,Visual Cortex Secondary,Visual Cortex V2,Visual Cortex V3,Visual Cortex V3, V4, V5,Visual Cortex V4,Visual Cortex V5,Visual Cortex, Associative,Visual Motion Area,Extrastriate Cortex,Area 18, Brodmann,Area 18, Brodmann's,Area 19, Brodmann,Area 19, Brodmann's,Area V2, Cortical,Area V3, Cortical,Area V4, Cortical,Area V5, Cortical,Area, Visual Motion,Associative Visual Cortices,Brodmanns Area 18,Brodmanns Area 19,Cortex Secondary, Visual,Cortex V2, Visual,Cortex V3, Visual,Cortex, Associative Visual,Cortex, Extrastriate,Cortex, Secondary Visual,Cortex, Visual,Cortical Area V3s,Extrastriate Cortices,Secondary Visual Cortices,V3, Cortical Area,V3, Visual Cortex,V4, Area,V4, Cortical Area,V5, Area,V5, Cortical Area,V5, Visual Cortex,Visual Cortex Secondaries,Visual Cortex, Secondary,Visual Motion Areas
D014796 Visual Perception The selecting and organizing of visual stimuli based on the individual's past experience. Visual Processing,Perception, Visual,Processing, Visual

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