There are concerns with feeding young dairy calves amounts of milk solids approaching 0.9kg of dry matter (DM) or more because of slumps in average daily gain (ADG) at weaning and low starter intakes. Additionally, programs feeding more than 0.6kg of DM have not been thoroughly tested for success at different weaning ages. Four milk replacer (MR) programs were compared in trial 1. Program A was 0.44kg of DM of a 21% crude protein (CP), 21% fat MR powder fed daily for 42 d. Program B was 0.66kg of DM of a 27% CP, 17% fat MR powder fed daily for 42 d. Program C was 0.66kg of DM of a 27% CP, 17% fat MR powder daily fed for 28 d. Program D was up to 1.09kg of DM of a 29% CP, 21% fat MR daily fed for 49 d. Digestibility estimates were made and blood was sampled for serum constituents on d 53 to 56, and performance was measured for 84 d. Three programs feeding a 27% CP, 17% fat MR powder were compared in trial 2 over 56 d. Calves on program A were fed 0.66kg of DM powder daily and weaned at 28 d. Calves on program B were fed 0.66kg of DM powder daily and weaned at 42 d. Calves on program C were fed up to 1.09kg of DM powder daily and weaned at 42 d. Digestibility estimates were made and blood was sampled for serum constituents d 21 to 24, d 36 to 39, and d 53 to 56. In trial 1, calves fed program A had the least overall ADG. Calves fed program D had the greatest ADG from 0 to 56 d, the least ADG from d 56 to 84, the least digestibility estimates, and the least concentrations of serum amylase. At 84 d, there were no differences in body weights of calves fed programs B, C, and D. In trial 2, calves fed program A had the greatest starter intake and greatest concentrations of serum amylase. Calves fed program C had the least estimates of digestibility from d 53 to 56 and the least serum concentrations of amylase. Calves fed up to 1.09 kg/d of 27 to 29% MR powders and weaned at 42 or 49 d had lower starter intakes, concentrations of serum amylase, and digestion of starter postweaning compared with calves fed conventional 21% CP, 21% fat MR powders fed at 0.44 kg/d. Calves fed 0.66 kg/d of a 27% CP, 17% fat MR powder and weaned at 28 or 42 d of age had no reductions in intake or digestion compared with calves fed conventional MR and gained as much total body weight from 0 to 84 d as calves stepped up to 1.09kg of MR.