A new stretch for muscle spindle research. 2010

Owen P Hamill
Department of Neuroscience and Cell Biology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, USA. ohamill@utmb.edu

UI MeSH Term Description Entries
D009446 Neurobiology The study of the structure, growth, activities, and functions of NEURONS and the NERVOUS SYSTEM. Cellular Neurobiology,Molecular Neurobiology,Neurobiology, Cellular,Neurobiology, Molecular
D009470 Muscle Spindles Skeletal muscle structures that function as the MECHANORECEPTORS responsible for the stretch or myotactic reflex (REFLEX, STRETCH). They are composed of a bundle of encapsulated SKELETAL MUSCLE FIBERS, i.e., the intrafusal fibers (nuclear bag 1 fibers, nuclear bag 2 fibers, and nuclear chain fibers) innervated by SENSORY NEURONS. Muscle Stretch Receptors,Neuromuscular Spindles,Receptors, Stretch, Muscle,Stretch Receptors, Muscle,Muscle Spindle,Muscle Stretch Receptor,Neuromuscular Spindle,Receptor, Muscle Stretch,Receptors, Muscle Stretch,Spindle, Muscle,Spindle, Neuromuscular,Spindles, Muscle,Spindles, Neuromuscular,Stretch Receptor, Muscle
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000584 Amiloride A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705) Amidal,Amiduret Trom,Amiloberag,Amiloride Hydrochloride,Amiloride Hydrochloride, Anhydrous,Kaluril,Midamor,Midoride,Modamide,Anhydrous Amiloride Hydrochloride,Hydrochloride, Amiloride,Hydrochloride, Anhydrous Amiloride,Trom, Amiduret
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D015220 Calcium Channels Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue. Ion Channels, Calcium,Receptors, Calcium Channel Blocker,Voltage-Dependent Calcium Channel,Calcium Channel,Calcium Channel Antagonist Receptor,Calcium Channel Antagonist Receptors,Calcium Channel Blocker Receptor,Calcium Channel Blocker Receptors,Ion Channel, Calcium,Receptors, Calcium Channel Antagonist,VDCC,Voltage-Dependent Calcium Channels,Calcium Channel, Voltage-Dependent,Calcium Channels, Voltage-Dependent,Calcium Ion Channel,Calcium Ion Channels,Channel, Voltage-Dependent Calcium,Channels, Voltage-Dependent Calcium,Voltage Dependent Calcium Channel,Voltage Dependent Calcium Channels
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D053503 Epithelial Sodium Channels Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. They are AMILORIDE-sensitive and play a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE. Epithelial Sodium Channel,Epithelial Sodium Ion Channels,ENaC (Epithelial Na+ Channel),ENaC alpha,ENaC beta,ENaC delta,ENaC gamma,Epithelial Amiloride-Sensitive Sodium Channel,Epithelial Sodium Channel, alpha Subunit,Epithelial Sodium Channel, beta Subunit,Epithelial Sodium Channel, delta Subunit,Epithelial Sodium Channel, gamma Subunit,SCNN1 alpha Subunit,SCNN1 beta Subunit,SCNN1 delta Subunit,SCNN1 gamma Subunit,Sodium Channel, Nonvoltage-gated 1 Protein, alpha Subunit,Sodium Channel, Nonvoltage-gated 1 Protein, beta Subunit,Sodium Channel, Nonvoltage-gated 1 Protein, delta Subunit,Sodium Channel, Nonvoltage-gated 1 Protein, gamma Subunit,Epithelial Amiloride Sensitive Sodium Channel,Sodium Channel, Epithelial,Sodium Channels, Epithelial,alpha Subunit, SCNN1
D062686 Epithelial Sodium Channel Blockers A subclass of sodium channel blockers that are specific for EPITHELIAL SODIUM CHANNELS. Epithelial Sodium Ion Channel Blockers,ENaC Channel Blockers,Epithelial Sodium Channel Antagonists,Epithelial Sodium Channel Inhibitors,Renal Epithelial Sodium Channel Blockers,Renal Epithelial Sodium Channel Inhibitors,Channel Blockers, ENaC
D018482 Muscle, Skeletal A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles. Anterior Tibial Muscle,Gastrocnemius Muscle,Muscle, Voluntary,Plantaris Muscle,Skeletal Muscle,Soleus Muscle,Muscle, Anterior Tibial,Muscle, Gastrocnemius,Muscle, Plantaris,Muscle, Soleus,Muscles, Skeletal,Muscles, Voluntary,Skeletal Muscles,Tibial Muscle, Anterior,Voluntary Muscle,Voluntary Muscles

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