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The effect of normobaric hyperoxia on voluntary salt intake was investigated in 20 sham-operated and 11 carotid body-denervated SHR. While in sham-operated SHR the saline intake was enhanced during the whole hyperoxic period, the carotid body-denervated rats showed an increase in salt appetite only on the second and third day of hyperoxia. Water intake was not significantly different in sham-operated and carotid body-denervated SHR. These findings, together with our previous results, suggest that chemoreceptor activity determines salt appetite but not water intake in SHR.
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