Biomaterial Database

Electroencephalographic changes associated with bromethalin toxicosis in the dog. 1991

D C Dorman, and A J Parker, and W B Buck

Department of Veterinary Biosciences, College of Veterinary Medicine, University of Illinois, Urbana 61801.

Electroencephalogram (EEG) recordings were obtained before and during the clinical syndrome induced by a bromethalin rodenticide given to dogs. Nine dogs given 6.25 mg bromethalin/kg po developed clinical signs and EEG abnormalities 15 to 58 h postdosing. Predominant abnormal EEG changes included spike and spike-and-wave EEG patterns (66%), high voltage slow wave (HVSA, 50-150 microV, 1-6 Hz) activity (44%) photoconvulsive or photoparoxysmal irritative responses (44%), and marked voltage depression (dominant activity less than 10 microV) in all leads (33%).

UI	MeSH Term	Description	Entries
D001927	Brain Diseases	Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.	Intracranial Central Nervous System Disorders,Brain Disorders,CNS Disorders, Intracranial,Central Nervous System Disorders, Intracranial,Central Nervous System Intracranial Disorders,Encephalon Diseases,Encephalopathy,Intracranial CNS Disorders,Brain Disease,Brain Disorder,CNS Disorder, Intracranial,Encephalon Disease,Encephalopathies,Intracranial CNS Disorder
D001931	Brain Mapping	Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.	Brain Electrical Activity Mapping,Functional Cerebral Localization,Topographic Brain Mapping,Brain Mapping, Topographic,Functional Cerebral Localizations,Mapping, Brain,Mapping, Topographic Brain
D004283	Dog Diseases	Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.	Canine Diseases,Canine Disease,Disease, Canine,Disease, Dog,Diseases, Canine,Diseases, Dog,Dog Disease
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D004569	Electroencephalography	Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.	EEG,Electroencephalogram,Electroencephalograms
D000814	Aniline Compounds	Compounds that include the aminobenzene structure.	Phenylamine,Phenylamines,Anilines,Compounds, Aniline
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012378	Rodenticides	Substances used to destroy or inhibit the action of rats, mice, or other rodents.	Rodenticide

Related Publications

D C Dorman, and A J Parker, and W B Buck

Diagnosis of bromethalin toxicosis in the dog.

April 1990, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc,

D C Dorman, and A J Parker, and W B Buck

Successful Management of Severe Bromethalin Toxicosis in a Dog.

January 2019, Journal of the American Animal Hospital Association,

D C Dorman, and A J Parker, and W B Buck

Neuropathology of feral conures with bromethalin toxicosis.

May 2022, Veterinary pathology,

D C Dorman, and A J Parker, and W B Buck

Neuropathologic findings of bromethalin toxicosis in the cat.

March 1992, Veterinary pathology,

D C Dorman, and A J Parker, and W B Buck

Pancreatic fibrosis associated with zinc toxicosis in a dog.

January 1991, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc,

D C Dorman, and A J Parker, and W B Buck

Bromethalin Exposure and Possible Toxicosis in a Bald Eagle (Haliaeetus leucocephalus).

October 2023, Journal of wildlife diseases,

D C Dorman, and A J Parker, and W B Buck

Evidence of bromethalin toxicosis in feral San Francisco "Telegraph Hill" conures.

January 2019, PloS one,

D C Dorman, and A J Parker, and W B Buck

[Electroencephalographic changes in the course of toxicosis, in relation to biological disorders].

January 1955, La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris,

D C Dorman, and A J Parker, and W B Buck

Severe Rhabdomyolysis Associated with Acute Amphetamine Toxicosis in a Dog.

January 2020, Case reports in veterinary medicine,