Biomaterial Database

Gastric arterio-venous shunts. An investigation using a dye dilution technique. 1967

P R Bell

University Department of Surgery, The Western Infirmary, Glasgow, Scotland.

The function of gastric submucosal A-V shunts has been investigated in dogs by the injection of a bolus of dye into the arterial side of the gastric circulation and its subsequent collection from the veins so that a dilution curve is obtained of its passage across the gastric vascular bed. Evidence of shunt activity has to be taken as a rapid transit time or double peak curves. Results suggest that under basal conditions evidence of functional A-V shunts has been found in some animals. Histamine appears to close shunts if they are open and divert blood through other slower channels. Adrenaline, vagal stimulation, vagotomy, and hepatic anoxia have not been found to have any effect on shunt activity. No evidence has been found to support the view that shunts respond in a uniform manner to control mucosal blood flow.

UI	MeSH Term	Description	Entries
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D004395	Dye Dilution Technique	Method for assessing flow through a system by injection of a known quantity of dye into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)	Dye Dilution Technic,Dilution Technic, Dye,Dilution Technics, Dye,Dilution Technique, Dye,Dilution Techniques, Dye,Dye Dilution Technics,Dye Dilution Techniques,Technic, Dye Dilution,Technics, Dye Dilution,Technique, Dye Dilution,Techniques, Dye Dilution
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001163	Arteriovenous Anastomosis	A vessel that directly interconnects an artery and a vein, and that acts as a shunt to bypass the CAPILLARY BEDS. Not to be confused with SURGICAL ANASTOMOSIS or ARTERIOVENOUS FISTULA.	Arteriovenous Anastomoses,Anastomose, Arteriovenous,Anastomoses, Arteriovenous,Anastomosis, Arteriovenous,Arteriovenous Anastomose
D013152	Splanchnic Circulation	The circulation of blood through the BLOOD VESSELS supplying the abdominal VISCERA.	Mesenteric Circulation,Circulation, Mesenteric,Circulation, Splanchnic,Circulations, Mesenteric,Circulations, Splanchnic,Mesenteric Circulations,Splanchnic Circulations
D013270	Stomach	An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.	Stomachs