Early assessment of nerve degeneration using the antidromic facial nerve response. 2010

Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
Department of Otolaryngology, Kochi Medical School, Nankoku, Kochi, Japan. hnakatan@tcc.pref.tochigi.lg.jp

CONCLUSIONS The antidromic facial nerve response (AFNR) is recommended as a monitoring method to detect cases resulting in facial nerve degeneration within 1 week after onset in patients with Bell's palsy and Hunt syndrome. OBJECTIVE The purpose of this study was to establish criteria for the AFNR to predict the prognosis of Bell's palsy and Hunt syndrome in the early stages, not exceeding 1 week after onset. METHODS 54 patients, including 40 with Bell's palsy and 14 with Hunt syndrome, were examined in this study. All patients were tested for the AFNR within 1 week after onset of paralysis and AFNR waveforms were analyzed. Four AFNR parameters, the total (peak-to-peak) amplitude (T-amp), the amplitudes of the positive wave (P-amp) and the negative wave (N-amp), and the N-amp/T-amp (N/T) ratio, were compared with the outcomes of facial paralysis. RESULTS In most patients with poor outcomes, T-amp was <4 microV and N-amp was <2 microV. The mean value of the N/T ratio in patients with a poor outcome fell to <0.4 after the 3rd day from onset, while that in patients with a good outcome was stable between 0.4 and 0.6 during the first week.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009410 Nerve Degeneration Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways. Neuron Degeneration,Degeneration, Nerve,Degeneration, Neuron,Degenerations, Nerve,Degenerations, Neuron,Nerve Degenerations,Neuron Degenerations
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D004568 Electrodiagnosis Diagnosis of disease states by recording the spontaneous electrical activity of tissues or organs or by the response to stimulation of electrically excitable tissue. Electrodiagnoses
D005154 Facial Nerve The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and SALIVARY GLANDS, and convey afferent information for TASTE from the anterior two-thirds of the TONGUE and for TOUCH from the EXTERNAL EAR. Cranial Nerve VII,Marginal Mandibular Branch,Marginal Mandibular Nerve,Seventh Cranial Nerve,Nerve VII,Nerve of Wrisberg,Nervus Facialis,Nervus Intermedius,Nervus Intermedius of Wrisberg,Cranial Nerve VIIs,Cranial Nerve, Seventh,Facial Nerves,Mandibular Nerve, Marginal,Mandibular Nerves, Marginal,Marginal Mandibular Nerves,Nerve VIIs,Nerve, Facial,Nerve, Marginal Mandibular,Nerve, Seventh Cranial,Nerves, Marginal Mandibular,Nervus Faciali,Seventh Cranial Nerves,Wrisberg Nerve,Wrisberg Nervus Intermedius
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
July 1999, The American journal of otology,
Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
November 1999, The American journal of otology,
Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
January 1987, American journal of otolaryngology,
Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
December 1994, European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery,
Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
May 1965, Archives of otolaryngology (Chicago, Ill. : 1960),
Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
December 1988, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery,
Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
January 1998, The Annals of otology, rhinology, and laryngology,
Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
April 1985, Neurosurgery,
Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
January 1988, Acta oto-laryngologica. Supplementum,
Hiroaki Nakatani, and Mitsuru Iwai, and Masashi Hamada, and Kazuhiro Yamakawa, and Akinobu Kakigi, and Taizo Takeda
September 1996, The American journal of otology,
Copied contents to your clipboard!