Null allele in a human polymorphism restricted to the placenta: call for a search. 1991

M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
Departamento de Medicina Preventiva, Universidade Federal da Bahia, Brazil.

The identification of a null allele in a human genetic system restricted to the placenta is a great challenge for two reasons: the impossibility of carrying out family studies and the unviability of sample recollections because the placenta itself is a disposable universe. Thus, in addition to reporting the finding of a null phenotype of placental alkaline phosphatase in a dark mulatto newborn from a black mixed population of Bahia, Brazil, here we present other evidence for the presence of the ALPP*Q0 allele with considerably high frequency in this population.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007527 Isoenzymes Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics. Alloenzyme,Allozyme,Isoenzyme,Isozyme,Isozymes,Alloenzymes,Allozymes
D008957 Models, Genetic Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment. Genetic Models,Genetic Model,Model, Genetic
D010641 Phenotype The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment. Phenotypes
D010920 Placenta A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES). Placentoma, Normal,Placentome,Placentas,Placentomes
D011110 Polymorphism, Genetic The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level. Gene Polymorphism,Genetic Polymorphism,Polymorphism (Genetics),Genetic Polymorphisms,Gene Polymorphisms,Polymorphism, Gene,Polymorphisms (Genetics),Polymorphisms, Gene,Polymorphisms, Genetic
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D001938 Brazil A country located on the eastern coast of South America, located between Colombia and Peru, that borders the Atlantic Ocean. It is bordered on the north by Venezuela, Guyana, Suriname, and French Guiana, on the south by Uruguay, and on the west by Argentina. The capital is Brasilia.
D005260 Female Females
D005787 Gene Frequency The proportion of one particular in the total of all ALLELES for one genetic locus in a breeding POPULATION. Allele Frequency,Genetic Equilibrium,Equilibrium, Genetic,Allele Frequencies,Frequencies, Allele,Frequencies, Gene,Frequency, Allele,Frequency, Gene,Gene Frequencies

Related Publications

M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
July 1980, American journal of human genetics,
M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
January 2015, Human heredity,
M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
October 1993, Journal of the American Academy of Dermatology,
M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
March 1973, Biochemical genetics,
M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
April 1984, Molecular biology and evolution,
M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
September 2003, Drug metabolism and disposition: the biological fate of chemicals,
M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
October 2022, Trends in genetics : TIG,
M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
January 2010, Molecular biology reports,
M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
December 1993, Human molecular genetics,
M C Silva, and M G Sousa, and R D Carvalho, and M R Passos-Bueno, and E S Azevêdo
January 2017, Journal of immunology (Baltimore, Md. : 1950),
Copied contents to your clipboard!