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Visualization of macromolecular structures. 2010
Seán I O'Donoghue, and
David S Goodsell, and
Achilleas S Frangakis, and
Fabrice Jossinet, and
Roman A Laskowski, and
Michael Nilges, and
Helen R Saibil, and
Andrea Schafferhans, and
Rebecca C Wade, and
Eric Westhof, and
Arthur J Olson
European Molecular Biology Laboratory, Heidelberg, Germany. sean.odonoghue@embl.de
Structural biology is rapidly accumulating a wealth of detailed information about protein function, binding sites, RNA, large assemblies and molecular motions. These data are increasingly of interest to a broader community of life scientists, not just structural experts. Visualization is a primary means for accessing and using these data, yet visualization is also a stumbling block that prevents many life scientists from benefiting from three-dimensional structural data. In this review, we focus on key biological questions where visualizing three-dimensional structures can provide insight and describe available methods and tools.
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Achilleas S Frangakis, and
Fabrice Jossinet, and
Roman A Laskowski, and
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Helen R Saibil, and
Andrea Schafferhans, and
Rebecca C Wade, and
Eric Westhof, and
Arthur J Olson
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Andrea Schafferhans, and
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Arthur J Olson
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Bioinformatics (Oxford, England),
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Fabrice Jossinet, and
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Andrea Schafferhans, and
Rebecca C Wade, and
Eric Westhof, and
Arthur J Olson
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FEBS letters,
Seán I O'Donoghue, and
David S Goodsell, and
Achilleas S Frangakis, and
Fabrice Jossinet, and
Roman A Laskowski, and
Michael Nilges, and
Helen R Saibil, and
Andrea Schafferhans, and
Rebecca C Wade, and
Eric Westhof, and
Arthur J Olson
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Molecular informatics,
