-transparent.png){kind=logo}
The formation of free radicals, which was represented by the concentration of free radicals in state 4 respiration, and the respiratory control ratio were studied in the myocardial mitochondria isolated from dog hearts that were failing due to aortic constriction. Both formation and respiratory control ratio were lowered, compared to each control value, in acute and chronic heart failure. A positive correlation was recognized between free radicals in state 4 respiration and respiratory control ratio. From these results it was concluded that there was uncoupling of oxidative phosphorylation in the mitochondria isolated from failing dog hearts. Measurement of free radicals in state 4 respiration, as well as respiratory control ratio, is a useful method for evaluation of the function of oxidative phosphorylation.
Y Suzuki, and
N Yamazaki, and
K Ogawa, and
K Mizutani, and
N Kakizawa
June 1975,
Japanese circulation journal,
Y Suzuki, and
N Yamazaki, and
K Ogawa, and
K Mizutani, and
N Kakizawa
January 1973,
Japanese circulation journal,
Y Suzuki, and
N Yamazaki, and
K Ogawa, and
K Mizutani, and
N Kakizawa
August 2004,
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
Y Suzuki, and
N Yamazaki, and
K Ogawa, and
K Mizutani, and
N Kakizawa
January 2008,
Molecular nutrition & food research,
Y Suzuki, and
N Yamazaki, and
K Ogawa, and
K Mizutani, and
N Kakizawa
January 1971,
Folia histochemica et cytochemica,
Y Suzuki, and
N Yamazaki, and
K Ogawa, and
K Mizutani, and
N Kakizawa
November 1976,
Physics in medicine and biology,
Y Suzuki, and
N Yamazaki, and
K Ogawa, and
K Mizutani, and
N Kakizawa
September 1991,
Forensic science international,
Y Suzuki, and
N Yamazaki, and
K Ogawa, and
K Mizutani, and
N Kakizawa
January 1991,
Advances in experimental medicine and biology,
Y Suzuki, and
N Yamazaki, and
K Ogawa, and
K Mizutani, and
N Kakizawa
October 1968,
Doklady Akademii nauk SSSR,
Y Suzuki, and
N Yamazaki, and
K Ogawa, and
K Mizutani, and
N Kakizawa
January 1987,
The Kurume medical journal,
