Selective ruthenium-catalyzed N-alkylation of indoles by using alcohols.
2010
Sebastian Bähn, and
Sebastian Imm, and
Kathleen Mevius, and
Lorenz Neubert, and
Annegret Tillack, and
Jonathan M J Williams, and
Matthias Beller
Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Str. 29a, 18059 Rostock, Germany.
UI
MeSH Term
Description
Entries
D007211
Indoles
Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.
D002384
Catalysis
The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.
Catalyses
D006865
Hydrogenation
Addition of hydrogen to a compound, especially to an unsaturated fat or fatty acid. (From Stedman, 26th ed)
Hydrogenations
D000438
Alcohols
Alkyl compounds containing a hydroxyl group. They are classified according to relation of the carbon atom: primary alcohols, R-CH2OH; secondary alcohols, R2-CHOH; tertiary alcohols, R3-COH. (From Grant & Hackh's Chemical Dictionary, 5th ed)
D000478
Alkylation
The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group.
Alkylations
D012428
Ruthenium
A hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.
D041961
Deuterium Exchange Measurement
A research technique to measure solvent exposed regions of molecules that is used to provide insight about PROTEIN CONFORMATION.