-transparent.png){kind=logo}
1. Rats were injected with a single dose of 35mg of streptozotocin/kg body wt. They exhibited a diabetes that was characterized by glycosuria, polyuria, polydipsia, hyperphagia, hyperglycaemia, increased concentrations of unesterified fatty acids, glycerol and triacylglycerols in the serum and an increased activity of glucose 6-phosphatase in the liver. 2. After 10 weeks the hepatic activities of the microsomal glycerol phosphate acyltransferase, phosphatidate phosphohydrolase, phosphatidate cytidylyltransferase, diacylglycerol acyltransferase, choline phosphotransferase, CDP-diacylglycerol--inositol phosphatidyltransferase and the soluble phosphatidate phosphohydrolase were measured. 3. The only significant changes were an increase in the activity of the soluble phosphatidate phosphohydrolase and a decrease in that of the CDP-diacylglycerol--inositol phosphatidyltransferase in the diabetic rats. 4. These results are discussed in relation to the control of glycerolipid synthesis.
P H Whiting, and
M Bowley, and
R G Sturton, and
P H Pritchard, and
D N Brindley, and
J N Hawthorne
December 1981,
Biochimica et biophysica acta,
P H Whiting, and
M Bowley, and
R G Sturton, and
P H Pritchard, and
D N Brindley, and
J N Hawthorne
August 1978,
The Biochemical journal,
P H Whiting, and
M Bowley, and
R G Sturton, and
P H Pritchard, and
D N Brindley, and
J N Hawthorne
April 1982,
Biochemical pharmacology,
P H Whiting, and
M Bowley, and
R G Sturton, and
P H Pritchard, and
D N Brindley, and
J N Hawthorne
September 1977,
The Biochemical journal,
P H Whiting, and
M Bowley, and
R G Sturton, and
P H Pritchard, and
D N Brindley, and
J N Hawthorne
January 1978,
Enzyme,
P H Whiting, and
M Bowley, and
R G Sturton, and
P H Pritchard, and
D N Brindley, and
J N Hawthorne
June 2014,
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas,
P H Whiting, and
M Bowley, and
R G Sturton, and
P H Pritchard, and
D N Brindley, and
J N Hawthorne
June 1986,
The Journal of urology,
P H Whiting, and
M Bowley, and
R G Sturton, and
P H Pritchard, and
D N Brindley, and
J N Hawthorne
May 1982,
Biochemical and biophysical research communications,
P H Whiting, and
M Bowley, and
R G Sturton, and
P H Pritchard, and
D N Brindley, and
J N Hawthorne
April 2000,
IUBMB life,
P H Whiting, and
M Bowley, and
R G Sturton, and
P H Pritchard, and
D N Brindley, and
J N Hawthorne
April 2000,
European journal of biochemistry,
