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The activity of hexokinase, glucose-6-phosphatase and glucose-6-phosphoric dehydrogenase was studied in the liver of rats after one hour, one and five days after a single oral administration of organic phosphorus insecticide valekson. It was determined that administration of the preparation led to an increase of activity in the homogenate and solubilization of glucose-6-phosphatase, activation of glucose-6-phosphoric dehydrogenase and inhibition of hexokinase. The changes were maximum one hour after the administration of the compound. The results show that a decrease of the intensity of glucose-6-phosphate formation and metabolism is one of the pathogenetic factors in the development of valekson-induced intoxication.
U A Kuz'minskaia, and
L V Bersan, and
M V Pis'mennaia
January 1976,
Bioinorganic chemistry,
U A Kuz'minskaia, and
L V Bersan, and
M V Pis'mennaia
January 1966,
Voprosy meditsinskoi khimii,
U A Kuz'minskaia, and
L V Bersan, and
M V Pis'mennaia
December 1983,
Acta medica Okayama,
U A Kuz'minskaia, and
L V Bersan, and
M V Pis'mennaia
February 1978,
Endokrinologie,
U A Kuz'minskaia, and
L V Bersan, and
M V Pis'mennaia
January 1977,
Vestnik Akademii meditsinskikh nauk SSSR,
U A Kuz'minskaia, and
L V Bersan, and
M V Pis'mennaia
January 1967,
Comptes rendus des seances de la Societe de biologie et de ses filiales,
U A Kuz'minskaia, and
L V Bersan, and
M V Pis'mennaia
January 1974,
Voprosy meditsinskoi khimii,
U A Kuz'minskaia, and
L V Bersan, and
M V Pis'mennaia
January 1964,
Acta biologica et medica Germanica,
U A Kuz'minskaia, and
L V Bersan, and
M V Pis'mennaia
April 1968,
Bollettino della Societa italiana di biologia sperimentale,
U A Kuz'minskaia, and
L V Bersan, and
M V Pis'mennaia
November 1966,
Journal of clinical pathology,
