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Sister chromatid exchange (SCE) analysis is the most sensitive method for assessing chromosome damage induced by chemical mutagens. We report the SCE of peripheral blood lymphocytes in children with primary nephrotic syndrome (NS) treated with chlorambucil. Group I consisted of 20 normal children, group 2 of 14 children with primary NS who had never received a cytotoxic drug and group III of 7 children with primary NS who had received chlorambucil, which was discontinued 6-36 months prior to the study. Group IV consisted of 4 nephrotic children who were receiving chlorambucil therapy during the study. There was no significant increase in SCE in group III compared with group I or group II (P much greater than 0.05). A significant rise in SCE (P less than 0.05) was seen in all patients in group IV.
A Y Elzouki, and
K al-Nassar, and
M al-Ali, and
G Malik, and
F Elsharie, and
O P Jaiswal
June 1979,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
A Y Elzouki, and
K al-Nassar, and
M al-Ali, and
G Malik, and
F Elsharie, and
O P Jaiswal
January 1983,
Teratogenesis, carcinogenesis, and mutagenesis,
A Y Elzouki, and
K al-Nassar, and
M al-Ali, and
G Malik, and
F Elsharie, and
O P Jaiswal
May 1980,
American journal of human genetics,
A Y Elzouki, and
K al-Nassar, and
M al-Ali, and
G Malik, and
F Elsharie, and
O P Jaiswal
January 2023,
Methods in molecular biology (Clifton, N.J.),
A Y Elzouki, and
K al-Nassar, and
M al-Ali, and
G Malik, and
F Elsharie, and
O P Jaiswal
December 1987,
American journal of medical genetics,
A Y Elzouki, and
K al-Nassar, and
M al-Ali, and
G Malik, and
F Elsharie, and
O P Jaiswal
January 1977,
Annual review of genetics,
A Y Elzouki, and
K al-Nassar, and
M al-Ali, and
G Malik, and
F Elsharie, and
O P Jaiswal
January 2005,
Current protocols in cell biology,
A Y Elzouki, and
K al-Nassar, and
M al-Ali, and
G Malik, and
F Elsharie, and
O P Jaiswal
September 1985,
European journal of pediatrics,
A Y Elzouki, and
K al-Nassar, and
M al-Ali, and
G Malik, and
F Elsharie, and
O P Jaiswal
September 2002,
Journal of clinical periodontology,
A Y Elzouki, and
K al-Nassar, and
M al-Ali, and
G Malik, and
F Elsharie, and
O P Jaiswal
January 1989,
Folia haematologica (Leipzig, Germany : 1928),
