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Complement-fixing antibodies to parainfluenza 3 virus were found in Hartley strain [Cds: (HA)] guinea pigs from the authors' production colony. The prevalence and distribution of these antibodies were determined by testing guinea pigs of five age categories: 4 weeks, 8 weeks, 12 weeks, 6 months to 1 year, and over 1 year of age. Forty-seven percent (28 of 60) were positive to parainfluenza 3 antigen. Positive reactors were found in all age groups except those 8 weeks old. The 12-week-old group had the highest titers; the group over 1 year of age had the highest percentage of positives (92%). When 8-week-old guinea pigs were isolated, 55% were positive at some time between 8 and 34 weeks of age. The titers characteristically rose rapidly and then dropped slowly to low or undetectable levels. Four pairs of breeders over 6 months of age (most of whom were positive for parainfluenza 3 virus antibodies and, therefore, presumed to be immune to the virus) were isolated and allowed to breed. Their offspring were found to be free of complement-fixing antibodies to parainfluenza 3 virus.
B G Welch, and
E J Snow, and
J R Hegner, and
S R Adams, and
K D Quist
September 1969,
Journal of immunology (Baltimore, Md. : 1950),
B G Welch, and
E J Snow, and
J R Hegner, and
S R Adams, and
K D Quist
September 1969,
Vox sanguinis,
B G Welch, and
E J Snow, and
J R Hegner, and
S R Adams, and
K D Quist
August 1956,
Canadian journal of microbiology,
B G Welch, and
E J Snow, and
J R Hegner, and
S R Adams, and
K D Quist
October 1957,
Journal of immunology (Baltimore, Md. : 1950),
B G Welch, and
E J Snow, and
J R Hegner, and
S R Adams, and
K D Quist
January 1964,
Journal of immunology (Baltimore, Md. : 1950),
B G Welch, and
E J Snow, and
J R Hegner, and
S R Adams, and
K D Quist
August 1974,
Laboratory animal science,
B G Welch, and
E J Snow, and
J R Hegner, and
S R Adams, and
K D Quist
October 1956,
Journal of bacteriology,
B G Welch, and
E J Snow, and
J R Hegner, and
S R Adams, and
K D Quist
March 1965,
Immunochemistry,
B G Welch, and
E J Snow, and
J R Hegner, and
S R Adams, and
K D Quist
November 2021,
International journal of molecular sciences,
B G Welch, and
E J Snow, and
J R Hegner, and
S R Adams, and
K D Quist
October 1966,
Canadian journal of comparative medicine and veterinary science,
