BIOMAT Database Logo BIOMAT Database Logo

Chemical reactions of the nitrogen mustard gases; monosubstitution products of ethyl-bis (beta-chloroethyl)amine and methyl-bis (beta-chloroethyl)amine. 1946

C GOLUMBIC, and J S FRUTON, and M BERGMANN

UI MeSH Term Description Entries
D008466 Mechlorethamine A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. Chlorethazine,Chlormethine,Mechlorethamine Oxide,Mustine,Nitrogen Mustard,Nitrogen Mustard N-Oxide,Bis(2-chloroethyl)methylamine,Caryolysine,Cloramin,Embichin,Mechlorethamine Hydrochloride,Mechlorethamine Hydrochloride N-Oxide,Mechlorethamine N-Oxide,Methylchlorethamine,Mitomen,Mustargen,NSC-10107,NSC-762,Nitrogranulogen,Nitromin,Hydrochloride N-Oxide, Mechlorethamine,Hydrochloride, Mechlorethamine,Mechlorethamine Hydrochloride N Oxide,Mechlorethamine N Oxide,N-Oxide, Mechlorethamine Hydrochloride,N-Oxide, Nitrogen Mustard,NSC 10107,NSC 762,NSC10107,NSC762,Nitrogen Mustard N Oxide
D005021 Ethylamines Derivatives of ethylamine (the structural formula CH3CH2NH2).
D005740 Gases The vapor state of matter; nonelastic fluids in which the molecules are in free movement and their mean positions far apart. Gases tend to expand indefinitely, to diffuse and mix readily with other gases, to have definite relations of volume, temperature, and pressure, and to condense or liquefy at low temperatures or under sufficient pressure. (Grant & Hackh's Chemical Dictionary, 5th ed)
D000588 Amines A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed) Amine

Related Publications

C GOLUMBIC, and J S FRUTON, and M BERGMANN
Chemical reactions of nitrogen mustard gases; reactions of methyl-bis (Beta-chloroethyl)amine with hexamethylenetetramine.
July 1947, The Journal of organic chemistry,
C GOLUMBIC, and J S FRUTON, and M BERGMANN
Chemical reactions of the nitrogen mustard gases; the transformations of ethyl-bis(beta-chloroethyl)amine in water.
September 1946, The Journal of organic chemistry,
C GOLUMBIC, and J S FRUTON, and M BERGMANN
Chemical reactions of the nitrogen mustard gases; the composition of aged unbuffered solutions of methyl-bis(beta-chloroethyl)amine.
September 1946, The Journal of organic chemistry,
C GOLUMBIC, and J S FRUTON, and M BERGMANN
Chemical reactions of the nitrogen mustard gases; the transformations of tris(beta-chloroethyl)-amine in water.
September 1946, The Journal of organic chemistry,
C GOLUMBIC, and J S FRUTON, and M BERGMANN
Nitrogen mustard; the use in South Australia of methyl bis (beta chloroethyl) amine.
July 1949, The Medical journal of Australia,
C GOLUMBIC, and J S FRUTON, and M BERGMANN
Cytologic changes in bronchogenic carcinoma following treatment with nitrogen mustard (methyl-bis [beta-chloroethyl] amine).
December 1948, Archives of pathology,
C GOLUMBIC, and J S FRUTON, and M BERGMANN
Result of methyl-bis (beta-chloroethyl) amine hydrochloride therapy; a preliminary report of a nitrogen mustard.
January 1947, Proceedings [of the] annual meeting. Central Society for Clinical Research (U.S.),
C GOLUMBIC, and J S FRUTON, and M BERGMANN
[The effect of methyl-bis (beta-chloroethyl) amine (nitrogen mustard) on the granulopectic action of the reticuloendothelial system].
June 1952, Il Policlinico. Sezione medica,
C GOLUMBIC, and J S FRUTON, and M BERGMANN
[Effect of nitrogen mustard (methyl-bis-beta-chloroethyl amine hydrochloride) on passive cutaneous anaphylaxis in the guinea pig].
December 1951, Bollettino della Societa italiana di biologia sperimentale,
C GOLUMBIC, and J S FRUTON, and M BERGMANN
Nitrogen mustard therapy; use of methyl-bis (beta-chloroethyl) amine hydrochloride and tris (beta-chloroethyl) amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders.
September 1946, Journal of the American Medical Association,
Copied contents to your clipboard!