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The plasma lipid lowering effect of modified Anna Pavala Sindhooram (APSm) was tested in 30 patients with plasma lipid abnormalities and with symptomatic ischemic heart disease (IHD) in a double-blind cross-over design. HDL2 cholesterol and total HDL cholesterol were increased during APSm therapy leading to a reduction in the coronary risk index. Plasma cholesterol, LDL and VLDL cholesterol, triglycerides, phospholipids and free fatty acids were significantly reduced during APSm therapy while withdrawal of the drug led to a slow increase in these lipids. No adverse side effects were noticed. Some patients were able to reduce their daily doses of antihypertensive and vasodilator drugs during APSm therapy.
E R Shanmugasundaram, and
P Sundaram, and
K Srinivas, and
K R Shanmugasundaram, and
J R Shankaran
July 1983,
Journal of ethnopharmacology,
E R Shanmugasundaram, and
P Sundaram, and
K Srinivas, and
K R Shanmugasundaram, and
J R Shankaran
July 1988,
Pharmacological research communications,
E R Shanmugasundaram, and
P Sundaram, and
K Srinivas, and
K R Shanmugasundaram, and
J R Shankaran
December 1982,
Atherosclerosis,
E R Shanmugasundaram, and
P Sundaram, and
K Srinivas, and
K R Shanmugasundaram, and
J R Shankaran
July 1983,
Journal of ethnopharmacology,
E R Shanmugasundaram, and
P Sundaram, and
K Srinivas, and
K R Shanmugasundaram, and
J R Shankaran
October 1982,
Pharmacological research communications,
E R Shanmugasundaram, and
P Sundaram, and
K Srinivas, and
K R Shanmugasundaram, and
J R Shankaran
August 1984,
Pharmacological research communications,
E R Shanmugasundaram, and
P Sundaram, and
K Srinivas, and
K R Shanmugasundaram, and
J R Shankaran
October 1979,
Wiener medizinische Wochenschrift (1946),
E R Shanmugasundaram, and
P Sundaram, and
K Srinivas, and
K R Shanmugasundaram, and
J R Shankaran
March 2001,
Nihon rinsho. Japanese journal of clinical medicine,
E R Shanmugasundaram, and
P Sundaram, and
K Srinivas, and
K R Shanmugasundaram, and
J R Shankaran
August 1984,
Arquivos brasileiros de cardiologia,
E R Shanmugasundaram, and
P Sundaram, and
K Srinivas, and
K R Shanmugasundaram, and
J R Shankaran
September 1995,
Acta dermato-venereologica,
