Cytogenetic findings in cervical carcinoma. A statistical approach. 1991

C Sreekantaiah, and M De Braekeleer, and O Haas
Cancer Center of Genetrix, Scottsdale, Arizona.

Cytogenetic analysis with banding techniques was attempted in 150 cervical carcinomas, including in situ carcinoma, large cell keratinizing tumors, large cell nonkeratinizing tumors, small cell nonkeratinizing tumors, and adenocarcinomas. Monte Carlo simulations were used to determine which numerical and structural aberrations were nonrandomly involved in the tumorous process and to attempt to correlate specific abnormalities with specific histologic types. Results showed that several chromosomes are nonrandomly involved in cervical carcinomas and that some are more specifically associated with particular histologic subtypes. Therefore, cervical carcinoma appear to include a large spectrum of malignancies, each particular histologic type involving different genes. If some cytogenetic changes may be considered general events related to the carcinogenesis process, other rearrangements are presumably more specific processes arising in more committed stem cells.

UI MeSH Term Description Entries
D007621 Karyotyping Mapping of the KARYOTYPE of a cell. Karyotype Analysis Methods,Analysis Method, Karyotype,Analysis Methods, Karyotype,Karyotype Analysis Method,Karyotypings,Method, Karyotype Analysis,Methods, Karyotype Analysis
D011003 Ploidies The degree of replication of the chromosome set in the karyotype. Ploidy
D002278 Carcinoma in Situ A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. Carcinoma, Intraepithelial,Carcinoma, Preinvasive,Intraepithelial Neoplasms,Neoplasms, Intraepithelial,Intraepithelial Carcinoma,Intraepithelial Neoplasm,Neoplasm, Intraepithelial,Preinvasive Carcinoma
D002294 Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) Carcinoma, Epidermoid,Carcinoma, Planocellular,Carcinoma, Squamous,Squamous Cell Carcinoma,Carcinomas, Epidermoid,Carcinomas, Planocellular,Carcinomas, Squamous,Carcinomas, Squamous Cell,Epidermoid Carcinoma,Epidermoid Carcinomas,Planocellular Carcinoma,Planocellular Carcinomas,Squamous Carcinoma,Squamous Carcinomas,Squamous Cell Carcinomas
D002583 Uterine Cervical Neoplasms Tumors or cancer of the UTERINE CERVIX. Cancer of Cervix,Cancer of the Cervix,Cancer of the Uterine Cervix,Cervical Cancer,Cervical Neoplasms,Cervix Cancer,Cervix Neoplasms,Neoplasms, Cervical,Neoplasms, Cervix,Uterine Cervical Cancer,Cancer, Cervical,Cancer, Cervix,Cancer, Uterine Cervical,Cervical Cancer, Uterine,Cervical Cancers,Cervical Neoplasm,Cervical Neoplasm, Uterine,Cervix Neoplasm,Neoplasm, Cervix,Neoplasm, Uterine Cervical,Uterine Cervical Cancers,Uterine Cervical Neoplasm
D002869 Chromosome Aberrations Abnormal number or structure of chromosomes. Chromosome aberrations may result in CHROMOSOME DISORDERS. Autosome Abnormalities,Cytogenetic Aberrations,Abnormalities, Autosome,Abnormalities, Chromosomal,Abnormalities, Chromosome,Chromosomal Aberrations,Chromosome Abnormalities,Cytogenetic Abnormalities,Aberration, Chromosomal,Aberration, Chromosome,Aberration, Cytogenetic,Aberrations, Chromosomal,Aberrations, Chromosome,Aberrations, Cytogenetic,Abnormalities, Cytogenetic,Abnormality, Autosome,Abnormality, Chromosomal,Abnormality, Chromosome,Abnormality, Cytogenetic,Autosome Abnormality,Chromosomal Aberration,Chromosomal Abnormalities,Chromosomal Abnormality,Chromosome Aberration,Chromosome Abnormality,Cytogenetic Aberration,Cytogenetic Abnormality
D002872 Chromosome Deletion Actual loss of portion of a chromosome. Monosomy, Partial,Partial Monosomy,Deletion, Chromosome,Deletions, Chromosome,Monosomies, Partial,Partial Monosomies
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000230 Adenocarcinoma A malignant epithelial tumor with a glandular organization. Adenocarcinoma, Basal Cell,Adenocarcinoma, Granular Cell,Adenocarcinoma, Oxyphilic,Adenocarcinoma, Tubular,Adenoma, Malignant,Carcinoma, Cribriform,Carcinoma, Granular Cell,Carcinoma, Tubular,Adenocarcinomas,Adenocarcinomas, Basal Cell,Adenocarcinomas, Granular Cell,Adenocarcinomas, Oxyphilic,Adenocarcinomas, Tubular,Adenomas, Malignant,Basal Cell Adenocarcinoma,Basal Cell Adenocarcinomas,Carcinomas, Cribriform,Carcinomas, Granular Cell,Carcinomas, Tubular,Cribriform Carcinoma,Cribriform Carcinomas,Granular Cell Adenocarcinoma,Granular Cell Adenocarcinomas,Granular Cell Carcinoma,Granular Cell Carcinomas,Malignant Adenoma,Malignant Adenomas,Oxyphilic Adenocarcinoma,Oxyphilic Adenocarcinomas,Tubular Adenocarcinoma,Tubular Adenocarcinomas,Tubular Carcinoma,Tubular Carcinomas

Related Publications

C Sreekantaiah, and M De Braekeleer, and O Haas
June 1986, Minerva ginecologica,
C Sreekantaiah, and M De Braekeleer, and O Haas
June 1970, Journal of the National Cancer Institute,
C Sreekantaiah, and M De Braekeleer, and O Haas
June 1987, Cancer genetics and cytogenetics,
C Sreekantaiah, and M De Braekeleer, and O Haas
September 1996, Human pathology,
C Sreekantaiah, and M De Braekeleer, and O Haas
January 1967, Acta medica Philippina,
C Sreekantaiah, and M De Braekeleer, and O Haas
April 1995, Cancer genetics and cytogenetics,
C Sreekantaiah, and M De Braekeleer, and O Haas
January 1998, Cancer genetics and cytogenetics,
C Sreekantaiah, and M De Braekeleer, and O Haas
February 2007, Cancer genetics and cytogenetics,
C Sreekantaiah, and M De Braekeleer, and O Haas
April 1983, Minerva ginecologica,
C Sreekantaiah, and M De Braekeleer, and O Haas
February 1964, Rivista di ostetricia e ginecologia,
Copied contents to your clipboard!