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An ACTH-secreting pituitary adenoma within the sphenoid sinus. 2010
Kunihiro Suzuki, and
Yoshiyuki Hattori, and
Chie Aoki, and
Ayuko Nakano, and
Atsuko Tomizawa, and
Hiroyuki Kase, and
Kikuo Kasai
Department of Endocrinology and Metabolism, Dokkyo University School of Medicine, Tochigi. kuni-s@dokkyomed.ac.jp
A 68-year-old woman developed Cushingoid features three months prior to admission. She was found to have a markedly elevated plasma ACTH-cortisol level. Magnetic resonance imaging (MRI) revealed a mass in the left sphenoidal sinus, which had become enlarged to a point where it could not be removed by transsphenoidal surgery. We decided to proceed with radiation therapy to shrink the tumor. However, it was ineffective. Despite a reduction in serum cortisol levels using metyrapone, she died of septic shock. We describe a rare case of an ACTH-secreting pituitary adenoma within the sphenoid sinus.
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