Biomaterial Database

[Non-oculomotor eye involvement in Moebius sequence]. 2010

R Michels, and V Sturm, and M N Menke, and K Landau

Moebius sequence is a congenital disorder that not only affects the oculomotor system but also the eyes themselves. Ocular involvement might be sight-threatening and needs regular follow-up by an ophthalmologist.

UI	MeSH Term	Description	Entries
D007766	Lacrimal Apparatus Diseases	Diseases of the LACRIMAL APPARATUS.	Epiphora,Apparatus Disease, Lacrimal,Apparatus Diseases, Lacrimal,Disease, Lacrimal Apparatus,Diseases, Lacrimal Apparatus,Epiphoras,Lacrimal Apparatus Disease
D012030	Refractive Errors	Deviations from the average or standard indices of refraction of the eye through its dioptric or refractive apparatus.	Ametropia,Refractive Disorders,Ametropias,Disorder, Refractive,Disorders, Refractive,Error, Refractive,Errors, Refractive,Refractive Disorder,Refractive Error
D004172	Diplopia	A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.	Double Vision,Polyopsia,Diplopia, Cortical,Diplopia, Horizontal,Diplopia, Intermittent,Diplopia, Monocular,Diplopia, Refractive,Diplopia, Unilateral,Diplopia, Vertical,Cortical Diplopia,Cortical Diplopias,Diplopias,Diplopias, Cortical,Diplopias, Horizontal,Diplopias, Intermittent,Diplopias, Monocular,Diplopias, Refractive,Diplopias, Unilateral,Diplopias, Vertical,Horizontal Diplopia,Horizontal Diplopias,Intermittent Diplopia,Intermittent Diplopias,Monocular Diplopia,Monocular Diplopias,Polyopsias,Refractive Diplopia,Refractive Diplopias,Unilateral Diplopia,Unilateral Diplopias,Vertical Diplopia,Vertical Diplopias,Vision, Double
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000550	Amblyopia	A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications.	Anisometropic Amblyopia,Lazy Eye,Amblyopia, Developmental,Amblyopia, Stimulus Deprivation-Induced,Amblyopia, Suppression,Stimulus Deprivation-Induced Amblyopia,Amblyopia, Anisometropic,Amblyopia, Stimulus Deprivation Induced,Amblyopias,Amblyopias, Anisometropic,Amblyopias, Developmental,Amblyopias, Stimulus Deprivation-Induced,Amblyopias, Suppression,Anisometropic Amblyopias,Deprivation-Induced Amblyopia, Stimulus,Deprivation-Induced Amblyopias, Stimulus,Developmental Amblyopia,Developmental Amblyopias,Eye, Lazy,Eyes, Lazy,Lazy Eyes,Stimulus Deprivation Induced Amblyopia,Stimulus Deprivation-Induced Amblyopias,Suppression Amblyopia,Suppression Amblyopias
D013666	Tears	The fluid secreted by the lacrimal glands. This fluid moistens the CONJUNCTIVA and CORNEA.	Meibomian Lipids,Meibum,Lipid, Meibomian,Meibomian Lipid,Tear
D020330	Bell Palsy	A syndrome characterized by the acute onset of unilateral FACIAL PARALYSIS which progresses over a 2-5 day period. Weakness of the orbicularis oculi muscle and resulting incomplete eye closure may be associated with corneal injury. Pain behind the ear often precedes the onset of paralysis. This condition may be associated with HERPESVIRUS 1, HUMAN infection of the facial nerve. (Adams et al., Principles of Neurology, 6th ed, p1376)	Bell's Palsy,Facial Neuropathy, Inflammatory, Acute,Facial Paralysis, Idiopathic,Herpetic Facial Paralysis,Acute Idiopathic Facial Neuropathy,Acute Inflammatory Facial Neuropathy,Facial Neuropathy, Idiopathic Acute,Idiopathic Acute Facial Neuropathy,Inflammatory Facial Neuropathy, Acute,Bell Palsies,Bell's Palsies,Bells Palsy,Facial Paralyses, Herpetic,Facial Paralyses, Idiopathic,Facial Paralysis, Herpetic,Herpetic Facial Paralyses,Idiopathic Facial Paralyses,Idiopathic Facial Paralysis,Palsies, Bell,Palsies, Bell's,Palsy, Bell,Palsy, Bell's,Paralyses, Herpetic Facial,Paralyses, Idiopathic Facial,Paralysis, Herpetic Facial,Paralysis, Idiopathic Facial
D020331	Mobius Syndrome	A syndrome of congenital facial paralysis, frequently associated with abducens palsy and other congenital abnormalities including lingual palsy, clubfeet, brachial disorders, cognitive deficits, and pectoral muscle defects. Pathologic findings are variable and include brain stem nuclear aplasia, facial nerve aplasia, and facial muscle aplasia, consistent with a multifactorial etiology. (Adams et al., Principles of Neurology, 6th ed, p1020)	Congenital Oculofacial Paralysis, Moebius,Congenital Ophthalmoplegia and Facial Paresis,Moebius Congenital Oculofacial Paralysis,Moebius Sequence,Moebius Spectrum,Moebius Syndrome,Möbius Sequence,Mobius Syndromes,Moebius Syndromes
D020433	Trigeminal Nerve Diseases	Diseases of the trigeminal nerve or its nuclei, which are located in the pons and medulla. The nerve is composed of three divisions: ophthalmic, maxillary, and mandibular, which provide sensory innervation to structures of the face, sinuses, and portions of the cranial vault. The mandibular nerve also innervates muscles of mastication. Clinical features include loss of facial and intra-oral sensation and weakness of jaw closure. Common conditions affecting the nerve include brain stem ischemia, INFRATENTORIAL NEOPLASMS, and TRIGEMINAL NEURALGIA.	Cranial Nerve V Diseases,Fifth Cranial Nerve Diseases,Raeder Paratrigeminal Syndrome,Trigeminal Nerve Disorders,Trigeminal Neuropathy,Trigeminal Neuropathy, Idiopathic,Idiopathic Trigeminal Neuropathies,Idiopathic Trigeminal Neuropathy,Neuropathies, Idiopathic Trigeminal,Neuropathies, Trigeminal,Neuropathy, Idiopathic Trigeminal,Neuropathy, Trigeminal,Syndrome, Raeder Paratrigeminal,Trigeminal Nerve Disease,Trigeminal Nerve Disorder,Trigeminal Neuropathies,Trigeminal Neuropathies, Idiopathic