Biomaterial Database

[Clinico-pathogenetic aspects of peptic ulcer therapy]. 1991

V V Chernin

Peptic ulcer therapy should be combined and take into consideration possible risk factors and the clinicopathogenetic aspects of the disease. The first stage involves the treatment of a relapse. It is to be carried out at hospital and to include protective regimen, diet, and agents that normalize disorders of nervous regulation, of secretory and motor functions of the stomach, endocrine shifts, drugs that relieve microcirculatory disorders and inflammatory phenomena, contributing to ulcer healing. The second stage involves reinforcement of the treatment results after the patients' discharge from hospital. The third stage involves carrying out of antirelapse measures. Such a principle of the patients' management enables reduction of the time of their stay at hospital by 6.2 days, increase of the percentage of ulcer healing from 76 to 94, reduction of the number of relapses by 2.5 times, decrease of the temporary disability by 3.4 times, and elimination of the disease complications.

UI	MeSH Term	Description	Entries
D010437	Peptic Ulcer	Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).	Gastroduodenal Ulcer,Marginal Ulcer,Gastroduodenal Ulcers,Marginal Ulcers,Peptic Ulcers,Ulcer, Gastroduodenal,Ulcer, Marginal,Ulcer, Peptic,Ulcers, Gastroduodenal,Ulcers, Marginal,Ulcers, Peptic
D012008	Recurrence	The return of a sign, symptom, or disease after a remission.	Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012307	Risk Factors	An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent.	Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor