-transparent.png){kind=logo}
Cloned antigens from Plasmodium falciparum as malaria vaccine candidates. 1991
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
Central Research Unit, F. Hoffmann-La Roche Ltd., Basle, Switzerland.
The problems of genetic polymorphism and poor immunogenicity of malaria vaccine candidates are discussed, with emphasis on the Circumsporozoite (CS) and p190 proteins of Plasmodium falciparum. It may be possible to use conserved regions of these proteins to raise protective immune responses against non-polymorphic determinants. Better adjuvants or delivery systems will be a critical factor in development of an effective vaccine.
Related Publications
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
January 1991,
Acta Leidensia,
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
October 2014,
Cellular and molecular life sciences : CMLS,
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
March 1986,
Papua and New Guinea medical journal,
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
January 1992,
Memorias do Instituto Oswaldo Cruz,
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
January 2019,
Frontiers in immunology,
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
May 2024,
medRxiv : the preprint server for health sciences,
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
January 2018,
Molecular & cellular proteomics : MCP,
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
August 2021,
Scientific reports,
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
January 2024,
Biomolecules,
J R Pink, and
P Caspers, and
H Etlinger, and
M Guttinger, and
H Matile, and
R Reber, and
H J Schönfeld, and
F Sinigaglia, and
D Stüber, and
D Stürchler
March 2015,
Trends in parasitology,
