Biomaterial Database

Linear lupus erythematosus profundus in a child. 1991

J Tada, and J Arata, and H Katayama

Department of Dermatology, Okayama University Medical School, Japan.

A 9-year-old Japanese boy had a 6-year history of a linear eruption of the left leg. It was characterized histopathologically by an intense lymphocytic panniculitis, perivascular and periappendageal infiltrates of lymphocytes, and vacuolization of the basal cell layer. This case represents a clinical presentation of linear lupus erythematosus profundus not previously reported.

UI	MeSH Term	Description	Entries
D007868	Leg Dermatoses	A nonspecific term used to denote any cutaneous lesion or group of lesions, or eruptions of any type on the leg. (From Stedman, 25th ed)	Leg Dermatosis,Dermatoses, Leg,Dermatosis, Leg
D008179	Lupus Erythematosus, Discoid	A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur.	Lupus Erythematosus, Chronic Cutaneous,Lupus Erythematosus, Cutaneous, Chronic,Discoid Lupus Erythematosus
D008214	Lymphocytes	White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.	Lymphoid Cells,Cell, Lymphoid,Cells, Lymphoid,Lymphocyte,Lymphoid Cell
D008297	Male		Males
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005218	Fat Necrosis	A condition in which the death of adipose tissue results in neutral fats being split into fatty acids and glycerol.	Steatonecrosis,Fat Necroses,Necrosis, Fat,Steatonecroses
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001485	Basement Membrane	A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.	Basal Lamina,Basement Lamina,Lamina Densa,Lamina Lucida,Lamina Reticularis,Basement Membranes,Densas, Lamina,Lamina, Basal,Lamina, Basement,Lucida, Lamina,Membrane, Basement,Membranes, Basement,Reticularis, Lamina
D015435	Panniculitis, Lupus Erythematosus	A type of lupus erythematosus characterized by deep dermal or subcutaneous nodules, most often on the head, face, or upper arms. It is generally chronic and occurs most often in women between the ages of 20 and 45.	Lupus Erythematosus Profundus,Lupus Panniculitis,Lupus Erythematosus Panniculitis,Lupus Profundus,Lupus Erythematosus Panniculitides,Lupus Panniculitides,Panniculitides, Lupus,Panniculitides, Lupus Erythematosus,Panniculitis, Lupus