Biomaterial Database

[Intramuscular myxoma of intercostal muscle; report of a case]. 2010

Takashi Yoshioka, and Masahiko Muro, and Kenjiro Kumano, and Tetsumasa Yamashita, and Youhei Kurose, and Shinichirou Kubo, and Hiroki Nojima, and Kanyu Nakano, and Shinya Asami, and Hiroshi Sasaki, and Hitoshi Idani, and Hitoshi Kin, and Norihisa Takakura

Department of Surgery, Fukuyama City Hospital, Fukuyama, Japan.

A 72-year-old woman was reffered to our hospital for further examination of a tumor shadow in the left upper lung field which was detected in a mass screening chest X-ray. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a chest wall tumor located in the left 4th intercostal space. The lesion was suspected to be neurogenic tumor and CT-guided needle biopsy was performed. The tumor was consisted of spindle-shaped cells, but immunohistochemistry demonstrated no evidence of neurogenic tumor. As a possibility of malignant tumor could not denied, we performed tumor resection under video-assisted surgery. The lesion was not originated from nerves, but adhered to the intercostal muscle. Histologically, the tumor was consisted of spidle-shaped cells without atypia which sparsely proliferate in the myxoid stroma adjacent to intercostal muscle. In immunohistochemistry, tumor cells were positive for vimentin, and negative for desmin, S-100 protein, smooth muscle actin, CD34 and factor VIII. It was diagnosed as intramuscular myxoma. This histology in the intercostal muscle is extremely rare.

UI	MeSH Term	Description	Entries
D007366	Intercostal Muscles	Respiratory muscles that arise from the lower border of one rib and insert into the upper border of the adjoining rib, and contract during inspiration or respiration. (From Stedman, 25th ed)	Intercostal Muscle,Muscle, Intercostal,Muscles, Intercostal
D009232	Myxoma	A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primitive mesenchymal tissue. It occurs frequently intramuscularly where it may be mistaken for a sarcoma. It appears also in the jaws and the skin. (From Stedman, 25th ed)	Angiomyxoma,Angiomyxomas,Myxomas
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D019042	Muscle Neoplasms	Tumors or cancer located in muscle tissue or specific muscles. They are differentiated from NEOPLASMS, MUSCLE TISSUE which are neoplasms composed of skeletal, cardiac, or smooth muscle tissue, such as MYOSARCOMA or LEIOMYOMA.	Cancer of Muscle,Muscle Cancer,Cancer of the Muscle,Neoplasms, Muscle,Cancer, Muscle,Cancers, Muscle,Muscle Cancers,Muscle Neoplasm,Neoplasm, Muscle