-transparent.png){kind=logo}
[Effect of inclusion complexation of decanoic acid with alpha-cyclodextrin on rectal absorption of cefmetazole sodium suppository in rabbits]. 1991
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University, Hokkaido, Japan.
Inclusion complex of decanoic acid (DA) with alpha-cyclodextrin (alpha-CyD) was prepared as an additive of cefmetazole sodium (CMZ) suppository and rectally administered to rabbits. The resulting complexation was examined by the phase solubility method, differential scanning calorimetry (DSC) and X-ray diffractometry. Plasma concentration and AUC of CMZ after rectal administration of a suppository containing DA/alpha-CyD complex to rabbits increased more significantly than those with none additive.
Related Publications
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
October 1991,
Chemical & pharmaceutical bulletin,
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
October 1994,
Pharmaceutical research,
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
January 2016,
Journal of molecular graphics & modelling,
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
February 2020,
The journal of physical chemistry. B,
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
March 1984,
Journal of pharmaceutical sciences,
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
December 1986,
Journal of pharmacobio-dynamics,
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
August 1982,
Journal of pharmaceutical sciences,
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
August 1985,
Journal of pharmaceutical sciences,
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
October 1990,
Journal of pharmacobio-dynamics,
H Yanagi, and
N Ishikura, and
H Kenmotsu, and
N Yagi, and
K Goto, and
S Kato, and
S Sumiya, and
M Takada
May 2015,
International journal of molecular sciences,
