Artificial bacterial flagella for micromanipulation. 2010

Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
Institute of Robotics and Intelligent Systems, ETH Zurich, CH-8092, Zurich, Switzerland.

This article presents an overview of recent developments in artificial bacterial flagella (ABFs) and discusses challenges and opportunities in pursuing applications. These helical swimmers possess several advantageous characteristics, such as high swimming velocity and precise motion control indicating their potential for diverse applications. One application is the manipulation of small objects within liquid, which is the focus of this review. Preliminary results have shown that ABFs are capable of performing microobject manipulation either directly by mechanical contact or indirectly by generating a localized fluid flow. The latter approach can be used for batch manipulation without direct contact, also implying possibilities for flow control in lab-on-a-chip systems. Miniaturized helical swimmers are also promising for biomedical applications, such as targeted drug delivery and implantation or removal of tissues and other objects.

UI MeSH Term Description Entries
D008280 Magnetics The study of MAGNETIC PHENOMENA. Magnetic
D008846 Micromanipulation The performance of dissections, injections, surgery, etc., by the use of micromanipulators (attachments to a microscope) that manipulate tiny instruments. Micromanipulations
D009038 Motion Physical motion, i.e., a change in position of a body or subject as a result of an external force. It is distinguished from MOVEMENT, a process resulting from biological activity. Motions
D005407 Flagella A whiplike motility appendage present on the surface cells. Prokaryote flagella are composed of a protein called FLAGELLIN. Bacteria can have a single flagellum, a tuft at one pole, or multiple flagella covering the entire surface. In eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella have the same basic structure as CILIA but are longer in proportion to the cell bearing them and present in much smaller numbers. (From King & Stansfield, A Dictionary of Genetics, 4th ed) Flagellum
D001419 Bacteria One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive. Eubacteria
D032701 Biomimetics An interdisciplinary field in materials science, ENGINEERING, and BIOLOGY, studying the use of biological principles for synthesis or fabrication of BIOMIMETIC MATERIALS. Mimetics, Biological,Bio-inspired Engineering,Biomimicry Engineering,Biomimicry Science,Bio inspired Engineering,Bio-inspired Engineerings,Biological Mimetic,Biological Mimetics,Biomimetic,Biomimicry Engineerings,Biomimicry Sciences,Engineering, Bio-inspired,Engineering, Biomimicry,Engineerings, Bio-inspired,Engineerings, Biomimicry,Mimetic, Biological,Science, Biomimicry,Sciences, Biomimicry

Related Publications

Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
May 2014, Small (Weinheim an der Bergstrasse, Germany),
Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
February 2016, Micromachines,
Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
August 2002, Nihon saikingaku zasshi. Japanese journal of bacteriology,
Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
January 1977, Annual review of microbiology,
Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
October 1951, Nature,
Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
October 1951, Nature,
Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
January 1971, Advances in microbial physiology,
Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
September 1966, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
June 2010, Proceedings of the National Academy of Sciences of the United States of America,
Li Zhang, and Kathrin E Peyer, and Bradley J Nelson
April 2010, Nature structural & molecular biology,
Copied contents to your clipboard!