Reported in this paper is a rare case of "amputation neuroma" of the cystic duct which had developed in the wake of cholecystectomy. The tumor had grown into the common bile duct over years and, eventually, had caused complete obliteration of the latter. Recurrent cholangitis had resulted in epigastric pain, febrile attacks, and icterus. Secondary biliary liver cirrhosis and a chronic biliodigestive fistula were additional complications. An acute cholangitis attack caused liver abscesses, and the patient died of septic shock.