Unusual findings in two patients with acquired deletions of the long arm of chromosome 5 (5q-). 1991

M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
Faculty of Medicine, University of Toronto, Ontario, Canada.

Two patients with acquired deletions of the long arm of chromosome 5 (5q-) are presented and discussed. For both, clinical and other laboratory tests are highly atypical of patients with haematological malignancy characterized by 5q-. These unusual presentations of the 5q- anomaly further emphasize the heterogeneity of clinical presentations associated with this acquired chromosomal abnormality.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009190 Myelodysplastic Syndromes Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA. Dysmyelopoietic Syndromes,Hematopoetic Myelodysplasia,Dysmyelopoietic Syndrome,Hematopoetic Myelodysplasias,Myelodysplasia, Hematopoetic,Myelodysplasias, Hematopoetic,Myelodysplastic Syndrome,Syndrome, Dysmyelopoietic,Syndrome, Myelodysplastic,Syndromes, Dysmyelopoietic,Syndromes, Myelodysplastic
D001853 Bone Marrow The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells. Marrow,Red Marrow,Yellow Marrow,Marrow, Bone,Marrow, Red,Marrow, Yellow
D002872 Chromosome Deletion Actual loss of portion of a chromosome. Monosomy, Partial,Partial Monosomy,Deletion, Chromosome,Deletions, Chromosome,Monosomies, Partial,Partial Monosomies
D002895 Chromosomes, Human, Pair 5 One of the two pairs of human chromosomes in the group B class (CHROMOSOMES, HUMAN, 4-5). Chromosome 5
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000753 Anemia, Refractory A severe sometimes chronic anemia, usually macrocytic in type, that does not respond to ordinary antianemic therapy. Refractory Anemia,Anemias, Refractory,Refractory Anemias

Related Publications

M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
January 1988, Przeglad lekarski,
M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
July 2012, Leukemia,
M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
November 1983, American journal of hematology,
M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
March 1988, American journal of medical genetics,
M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
February 1985, Cancer genetics and cytogenetics,
M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
October 2013, Leukemia & lymphoma,
M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
January 1984, Oncology,
M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
April 1979, Journal of medical genetics,
M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
February 1981, Annals of human genetics,
M Lishner, and D Amato, and P Chalvardjian, and M A Baker, and B Fernandes, and D Pantalony, and I D Dube
January 1985, American journal of medical genetics,
Copied contents to your clipboard!