[Tumor specific surface antigen in the culture medium of a rat cell line transformed by Rous sarcoma virus]. 1977

J C Laurent, and M Aupoix, and T Greenland, and V Krsmanovic

TSSA is detected on transformed cells by a mixed hemadsorption reaction. The medium of cultures of Rat cells transformed by Rous sarcoma virus (Prague strain, sub-group C) contains a soluble factor which specifically inhibits this reaction. This factor thus possesses the antigenic activity of TSSA which is associated with the presence of a component of molecular weight 42,000 by polyacrylamide gel electrophoresis.

UI MeSH Term Description Entries
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D002472 Cell Transformation, Viral An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus. Transformation, Viral Cell,Viral Cell Transformation,Cell Transformations, Viral,Transformations, Viral Cell,Viral Cell Transformations
D003470 Culture Media Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN. Media, Culture
D006383 Hemadsorption Inhibition Tests Serological tests that measure anti-hemadsorption agents such as antiviral ANTIBODIES that block VIRAL HEMAGGLUNININS from adhering to the surface of red blood cells. Hemadsorption Inhibition Test,Inhibition Test, Hemadsorption,Inhibition Tests, Hemadsorption,Test, Hemadsorption Inhibition,Tests, Hemadsorption Inhibition
D000951 Antigens, Neoplasm Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin. Neoplasm Antigens,Tumor Antigen,Tumor Antigens,Antigen, Tumor,Antigens, Tumor
D001358 Avian Sarcoma Viruses Group of alpharetroviruses (ALPHARETROVIRUS) producing sarcomata and other tumors in chickens and other fowl and also in pigeons, ducks, and RATS. Avian Sarcoma Virus B77,Chicken Sarcoma Virus B77,Chicken Tumor 1 Virus,Fujinami sarcoma virus,Sarcoma Viruses, Avian,Avian Sarcoma Virus,Fujinami sarcoma viruses,Sarcoma Virus, Avian,Virus, Avian Sarcoma,Viruses, Avian Sarcoma,sarcoma virus, Fujinami,virus, Fujinami sarcoma,viruses, Fujinami sarcoma

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