In vitro effects of Cassava (Manihot esculenta) leaf extracts on four development stages of Haemonchus contortus. 2010

C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
Institut National de la Recherche Agronomique, Unité de Recherches Zootechniques, Domaine de Duclos, 97170 Prise d'eau PETIT-BOURG, Guadeloupe (FWI). Carine.Marie-Magdeleine@antilles.inra.fr

Three extracts (aqueous, methanolic and dichloromethane) of Manihot esculenta (Cassava) leaf were tested in vitro on four development stages of Haemonchus contortus using egg hatch assay (EHA), larval development assay (LDA), L3 migration inhibition assay (LMI) and adult worm motility assay (AWM). Compared to the negative control, significant effects (P<0.0001) were observed for the methanolic extract of leaf against larval development (57.6% +/-7.6), with a dose dependent effect. These results suggest that Cassava possess anthelmintic activity against H. contortus. The active principles responsible for the activity could be the terpenoids and condensed tannin compounds present in the leaf.

UI MeSH Term Description Entries
D010063 Ovum A mature haploid female germ cell extruded from the OVARY at OVULATION. Egg,Egg, Unfertilized,Ova,Eggs, Unfertilized,Unfertilized Egg,Unfertilized Eggs
D010936 Plant Extracts Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard. Herbal Medicines,Plant Extract,Extract, Plant,Extracts, Plant,Medicines, Herbal
D002365 Manihot A plant genus of the family EUPHORBIACEAE that is perennial with conspicuous, almost palmate leaves like those of RICINUS but more deeply parted into five to nine lobes. It is a source of a starch after removal of the cyanogenic glucosides. The common name of Arrowroot is also used with Maranta (MARANTACEAE). The common name of yuca is also used for YUCCA. Arrowroot, Brazilian,Brazilian Arrowroot,Cassava,Kasaba,Manioc,Tapioca,Manihot esculenta,Arrowroots, Brazilian,Brazilian Arrowroots,Cassavas,Kasabas,Manihot esculentas,Manihots,Maniocs,Tapiocas,esculenta, Manihot
D006189 Haemonchus A genus of parasitic nematode worms which infest the duodenum and stomach of domestic and wild herbivores, which ingest it with the grasses (POACEAE) they eat. Infestation of man is accidental. Hemonchus
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000871 Anthelmintics Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal. Anthelmintic,Antihelmintic,Vermifuge,Vermifuges,Antihelmintics
D018515 Plant Leaves Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed) Plant Leaf,Leaf, Plant,Leave, Plant,Leaves, Plant,Plant Leave

Related Publications

C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
January 2015, Methods in molecular biology (Clifton, N.J.),
C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
January 2006, Methods in molecular biology (Clifton, N.J.),
C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
August 2010, Research in veterinary science,
C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
October 2013, Veterinary parasitology,
C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
April 2009, Veterinary parasitology,
C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
May 2014, AoB PLANTS,
C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
January 2011, African journal of traditional, complementary, and alternative medicines : AJTCAM,
C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
February 2003, Bioresource technology,
C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
January 2018, Anais da Academia Brasileira de Ciencias,
C Marie-Magdeleine, and L Udino, and L Philibert, and B Bocage, and H Archimede
January 2022, PloS one,
Copied contents to your clipboard!