This article briefly discusses the teaching of humanities at the Medicine course and presents a proposal developed at the Center of Medical Education Development (CEDEM) of the Medicine School of São Paulo University (Faculdade de Medicina da Universidade de São Paulo - FMUSP) for the integration of this area in the curriculum. The curricular integration is a strategy of education, based on the systemic vision that involves actions of wide educational range. The teaching of humanities in Medicine aims at approaching the techniques and the look at the human condition, as well as develops didactic-pedagogical methods to its learning. The proposal of integration presented in this article consists of six strategic actions, in different states of development: (1) Elaboration of the terminal objectives of the area for the student's formation, (2) Integration of six humanity disciplines of the current curriculum, (3) Integration of the humanistic subjects with others disciplines in accordance with the terminal objectives of the area, (4) Planning of teaching development courses in medical humanities, (5) Development of evaluation system and supervision of the humanistic formation, (6) Spreading of the "Humanities and Medicine" area.