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On the basis of the analysis of 39 pedigrees with syndactylies it is concluded an autosomal dominant mode of the inheritance with incomplete penetrance. The variability of penetrance is more pronounced in females who are frequently healthy carriers of the gene transmitting it to both sexes. The significant prevalence of males in syndactylies can be explained by deathes of female embryos in utero, the sex ratio in healthy sibses being normal.
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