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In an attempt to define the rate of endogenous secretion of parathyroid hormone in vitamin D deficiency, graded amounts of hormone were infused constantly into vitamin D deficient and vitamin D fed acutely thyroparathyroidectomized rats in a perfusion balance study. The dose of hormone needed to compensate for acute thyroparathyroidectomy was estimated. Serum levels of calcium and phosphorus, renal clearances of phosphorus and urinary excretion of cyclic AMP, each determined 16 hr after the surgery, were employed as parameters of the hormone effect. It was concluded that, in the condition of the perfusion balance study, the secretion rate of parathyroid hormone was 5.1-8.6 USP u/hr in the vitamin D deficient animals compared with 0.81-0.84 USP u/hr in the control.
H Takahashi, and
E Shimazawa, and
N Horiuchi, and
T Suda, and
K Yamashita, and
E Ogata
February 1984,
Nihon juigaku zasshi. The Japanese journal of veterinary science,
H Takahashi, and
E Shimazawa, and
N Horiuchi, and
T Suda, and
K Yamashita, and
E Ogata
December 1965,
The Journal of clinical investigation,
H Takahashi, and
E Shimazawa, and
N Horiuchi, and
T Suda, and
K Yamashita, and
E Ogata
January 1980,
Advances in experimental medicine and biology,
H Takahashi, and
E Shimazawa, and
N Horiuchi, and
T Suda, and
K Yamashita, and
E Ogata
January 1974,
Scandinavian journal of gastroenterology,
H Takahashi, and
E Shimazawa, and
N Horiuchi, and
T Suda, and
K Yamashita, and
E Ogata
November 1973,
The New England journal of medicine,
H Takahashi, and
E Shimazawa, and
N Horiuchi, and
T Suda, and
K Yamashita, and
E Ogata
May 1980,
Biochimica et biophysica acta,
H Takahashi, and
E Shimazawa, and
N Horiuchi, and
T Suda, and
K Yamashita, and
E Ogata
February 1979,
European journal of pediatrics,
H Takahashi, and
E Shimazawa, and
N Horiuchi, and
T Suda, and
K Yamashita, and
E Ogata
December 1980,
The Journal of biological chemistry,
H Takahashi, and
E Shimazawa, and
N Horiuchi, and
T Suda, and
K Yamashita, and
E Ogata
June 1997,
Endocrinology,
H Takahashi, and
E Shimazawa, and
N Horiuchi, and
T Suda, and
K Yamashita, and
E Ogata
March 1982,
Endocrinology,
