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Two independent mouse-human somatic cell hybrid clones contained different, de novo chromosome rearrangements involving the short arm of human chromosome 1. One hybrid clone contained a translocation between human chromosomes 1 and 7; the other clone contained a rearrangement product between human chromosomes 1 and 14. Analysis of these clones for expression of genes previously assigned to chromosome 7 and to the short arm of chromosome 1 provided evidence for localization of PGM--1 in segment 1p22.1 leads to 1p31.1, AK--2, ENO--1 and UMPK in region 1pter leads to 1p31.1, and GUS in region 7 pter leads to 7q22. The results have been used to examine the relationship between cytologic and genetic map distances on the short arm of chromosome 1.
D L George, and
U Francke
January 1975,
Cytogenetics and cell genetics,
D L George, and
U Francke
January 1979,
Cytogenetics and cell genetics,
D L George, and
U Francke
April 1977,
Biochemical genetics,
D L George, and
U Francke
July 1976,
American journal of human genetics,
D L George, and
U Francke
January 1981,
Cytogenetics and cell genetics,
D L George, and
U Francke
January 1978,
Cytogenetics and cell genetics,
D L George, and
U Francke
August 1987,
Proceedings of the National Academy of Sciences of the United States of America,
D L George, and
U Francke
March 1995,
Mammalian genome : official journal of the International Mammalian Genome Society,
D L George, and
U Francke
January 1976,
Cytogenetics and cell genetics,
D L George, and
U Francke
January 1976,
Birth defects original article series,
